A systematic approach to further improve stent-graft performance
Thoracic endovascular aortic repair (TEVAR) is limited by the complicated anatomy of an aortic arch. This study proposed a new stent-graft (SG) design with slits that can positively improve the sealing effect between the aorta and SG while maintaining blood flow to supra-aortic branches. Firstly, a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127521006997 |
| _version_ | 1818696042636378112 |
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| author | Zongchao Liu Shuai Teng Gongfa Chen Linhui Wu Junwei Yang Fangsen Cui Pei Ho |
| author_facet | Zongchao Liu Shuai Teng Gongfa Chen Linhui Wu Junwei Yang Fangsen Cui Pei Ho |
| author_sort | Zongchao Liu |
| collection | DOAJ |
| description | Thoracic endovascular aortic repair (TEVAR) is limited by the complicated anatomy of an aortic arch. This study proposed a new stent-graft (SG) design with slits that can positively improve the sealing effect between the aorta and SG while maintaining blood flow to supra-aortic branches. Firstly, a new SG was designed by changing the geometrical parameters (strut height, strut radius, strut diameter, etc.) based on previous research. The main mechanical performances of the SG were evaluated. Results showed that the new design improved the sealing effect and decreased the Type-Ι endoleak risk. The new design also had the comparable radial force, compression strength and fatigue life. Secondly, a fluid dynamic analysis was carried out in an ideal normal aortic arch model to evaluate the slit SG design. Satisfactory flow perfusion in branches was obtained, and no undesirable vortexes were found. Therefore, the hemodynamic environment in the aortic arch after the SG implantation was not significantly changed. The present study indicates that the design thought has a potential to deal with the technical difficulties of TEVAR at the aortic arch. This study provides the basis for potential optimization to obtain a more applicable SG design. |
| first_indexed | 2024-12-17T13:55:05Z |
| format | Article |
| id | doaj.art-a789730a8edd44b0979469297dbcd4fd |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-12-17T13:55:05Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-a789730a8edd44b0979469297dbcd4fd2022-12-21T21:45:56ZengElsevierMaterials & Design0264-12752021-12-01211110144A systematic approach to further improve stent-graft performanceZongchao Liu0Shuai Teng1Gongfa Chen2Linhui Wu3Junwei Yang4Fangsen Cui5Pei Ho6Guangdong University of Technology, ChinaGuangdong University of Technology, ChinaGuangdong University of Technology, China; Corresponding authors at: School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou 510006, China (G. Chen); Institute of High Performance Computing, A*STAR, Singapore 138632 (F. Cui).Guangdong University of Technology, ChinaGuangdong University of Technology, ChinaInstitute of High Performance Computing, A*STAR, Singapore; Corresponding authors at: School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou 510006, China (G. Chen); Institute of High Performance Computing, A*STAR, Singapore 138632 (F. Cui).Department of Surgery, National University of Singapore, SingaporeThoracic endovascular aortic repair (TEVAR) is limited by the complicated anatomy of an aortic arch. This study proposed a new stent-graft (SG) design with slits that can positively improve the sealing effect between the aorta and SG while maintaining blood flow to supra-aortic branches. Firstly, a new SG was designed by changing the geometrical parameters (strut height, strut radius, strut diameter, etc.) based on previous research. The main mechanical performances of the SG were evaluated. Results showed that the new design improved the sealing effect and decreased the Type-Ι endoleak risk. The new design also had the comparable radial force, compression strength and fatigue life. Secondly, a fluid dynamic analysis was carried out in an ideal normal aortic arch model to evaluate the slit SG design. Satisfactory flow perfusion in branches was obtained, and no undesirable vortexes were found. Therefore, the hemodynamic environment in the aortic arch after the SG implantation was not significantly changed. The present study indicates that the design thought has a potential to deal with the technical difficulties of TEVAR at the aortic arch. This study provides the basis for potential optimization to obtain a more applicable SG design.http://www.sciencedirect.com/science/article/pii/S0264127521006997Thoracic aortic archFinite element analysesMechanical propertiesComputational fluid dynamicsSlit |
| spellingShingle | Zongchao Liu Shuai Teng Gongfa Chen Linhui Wu Junwei Yang Fangsen Cui Pei Ho A systematic approach to further improve stent-graft performance Materials & Design Thoracic aortic arch Finite element analyses Mechanical properties Computational fluid dynamics Slit |
| title | A systematic approach to further improve stent-graft performance |
| title_full | A systematic approach to further improve stent-graft performance |
| title_fullStr | A systematic approach to further improve stent-graft performance |
| title_full_unstemmed | A systematic approach to further improve stent-graft performance |
| title_short | A systematic approach to further improve stent-graft performance |
| title_sort | systematic approach to further improve stent graft performance |
| topic | Thoracic aortic arch Finite element analyses Mechanical properties Computational fluid dynamics Slit |
| url | http://www.sciencedirect.com/science/article/pii/S0264127521006997 |
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