Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation
The establishment of separated pulmonary and systemic circulation in vertebrates, via cardiac outflow tract (OFT) septation, is a sensitive developmental process accounting for 10% of all congenital anomalies. Neural Crest Cells (NCC) colonising the heart condensate along the primitive endocardial t...
Main Authors: | Jean-François Darrigrand, Mariana Valente, Glenda Comai, Pauline Martinez, Maxime Petit, Ryuichi Nishinakamura, Daniel S Osorio, Gilles Renault, Carmen Marchiol, Vanessa Ribes, Bruno Cadot |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/50325 |
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