Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress

Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress

Cyclobutane pyrimidine dimers (CPDs) are the main mutagenic DNA photoproducts caused by ultraviolet B (UVB) radiation and represent the major cause of photoaging and skin carcinogenesis. CPD photolyase can efficiently and rapidly repair CPD products. Therefore, they are candidates for the prevention...

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Bibliographic Details
Main Authors: Zhaoyang Wang, Ziyi Li, Yaling Lei, Yuan Liu, Yuqing Feng, Derong Chen, Siying Ma, Ziyan Xiao, Meirong Hu, Jingxian Deng, Yuxin Wang, Qihao Zhang, Yadong Huang, Yan Yang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
recombinant photolyase
photorepair
DNA damage
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/11/12/2312

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