Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration

Advances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attr...

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Main Authors: Mohamadreza Baghaban Eslaminejad, Shahrbanoo Jahangir
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2012-10-01
Series:International Journal of Fertility and Sterility
Subjects:
Online Access:http://www.ijfs.ir/article_45138_0bd932ae125e5672f2443f30544ff4ba.pdf
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author Mohamadreza Baghaban Eslaminejad
Shahrbanoo Jahangir
author_facet Mohamadreza Baghaban Eslaminejad
Shahrbanoo Jahangir
author_sort Mohamadreza Baghaban Eslaminejad
collection DOAJ
description Advances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attracted attention as a viable choice following the search for an alternative stem cell source. Investigators are interested in these cells because they come from the amniotic fluid that is routinely discarded after birth. There have been multiple investigations conducted worldwide in an attempt to better understand AF-SCs in terms of their potential use in regenerative medicine. In this review we give a brief introduction of amniotic fluid followed by a description of the cells present within this fluid. Their history related to stem cell discovery in the amniotic fluid as well as the main characteristics of AF-SCs are discussed. Finally, we elaborate on the potential for these cells to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart, lungs, kidneys, bones, and cartilage.
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spelling doaj.art-a79136e3e0214e4587f3c25b5d75ff6a2022-12-21T18:30:59ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782012-10-016314715645138Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue RegenerationMohamadreza Baghaban EslaminejadShahrbanoo JahangirAdvances in stem cell biotechnology hold great promise in the field of tissue engineering and regenerative medicine. Of interest are marrow mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). In addition, amniotic fluid stem cells (AFSCs) have attracted attention as a viable choice following the search for an alternative stem cell source. Investigators are interested in these cells because they come from the amniotic fluid that is routinely discarded after birth. There have been multiple investigations conducted worldwide in an attempt to better understand AF-SCs in terms of their potential use in regenerative medicine. In this review we give a brief introduction of amniotic fluid followed by a description of the cells present within this fluid. Their history related to stem cell discovery in the amniotic fluid as well as the main characteristics of AF-SCs are discussed. Finally, we elaborate on the potential for these cells to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart, lungs, kidneys, bones, and cartilage.http://www.ijfs.ir/article_45138_0bd932ae125e5672f2443f30544ff4ba.pdfamniotic fluidstem cellsmesenchymal stem cellstissue regenerationtissue engineering
spellingShingle Mohamadreza Baghaban Eslaminejad
Shahrbanoo Jahangir
Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
International Journal of Fertility and Sterility
amniotic fluid
stem cells
mesenchymal stem cells
tissue regeneration
tissue engineering
title Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
title_full Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
title_fullStr Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
title_full_unstemmed Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
title_short Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration
title_sort amniotic fluid stem cells and their application in cell based tissue regeneration
topic amniotic fluid
stem cells
mesenchymal stem cells
tissue regeneration
tissue engineering
url http://www.ijfs.ir/article_45138_0bd932ae125e5672f2443f30544ff4ba.pdf
work_keys_str_mv AT mohamadrezabaghabaneslaminejad amnioticfluidstemcellsandtheirapplicationincellbasedtissueregeneration
AT shahrbanoojahangir amnioticfluidstemcellsandtheirapplicationincellbasedtissueregeneration