An optimized experimental strategy for efficient conversion of embryonic stem (ES)-derived mouse neural stem (NS) cells into a nearly homogeneous mature neuronal population

An optimized experimental strategy for efficient conversion of embryonic stem (ES)-derived mouse neural stem (NS) cells into a nearly homogeneous mature neuronal population

NS cells are a homogeneous population of neural stem cells which were previously derived from embryonic stem cells as well as from the fetal and adult brain. Our previous reports have described a 21 day long neuronal differentiation protocol able to reproducibly convert adult SVZ-derived NS (aNS) ce...

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Bibliographic Details
Main Authors: D. Spiliotopoulos, D. Goffredo, L. Conti, F. Di Febo, G. Biella, M. Toselli, E. Cattaneo
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Neurobiology of Disease
Subjects:
Neural differentiation
Neural stem cell
NS cells
In vitro differentiation
Neurons
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000291

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