The effectiveness of ursolic acid niosomes with chitosan coating for prevention of liver damage in mice induced by n-nitrosodiethylamine

The effectiveness of ursolic acid niosomes with chitosan coating for prevention of liver damage in mice induced by n-nitrosodiethylamine

Abstract Ursolic acid (UA) is a pentacyclic triterpene carboxylic acid which produces various effects, including anti-cancer, hepatoprotective, antioxidant and anti-inflammatory. However, UA demonstrates poor water solubility and permeability. Niosomes have been reported to improve the bioavailabili...

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Bibliographic Details
Main Authors: Andang Miatmoko, Amelia Anneke Faradisa, Achmad Aziz Jauhari, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Hani Plumeriastuti, Retno Sari, Esti Hendradi
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26085-2

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