Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report

Abstract Background Xanthogranulomatous inflammation is an uncommon condition in adult nasal cavity and nasopharynx. Case presentation We report a male patient who developed xanthogranulomatous inflammation in the bilateral nose and nasopharynx. The patient was not responsive to oral steroid. Multip...

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Main Authors: Wei Jie Boon, Khim Soon Vong, Ing Ping Tang
Format: Article
Language:English
Published: SpringerOpen 2022-01-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Online Access:https://doi.org/10.1186/s43163-022-00201-5
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author Wei Jie Boon
Khim Soon Vong
Ing Ping Tang
author_facet Wei Jie Boon
Khim Soon Vong
Ing Ping Tang
author_sort Wei Jie Boon
collection DOAJ
description Abstract Background Xanthogranulomatous inflammation is an uncommon condition in adult nasal cavity and nasopharynx. Case presentation We report a male patient who developed xanthogranulomatous inflammation in the bilateral nose and nasopharynx. The patient was not responsive to oral steroid. Multiple biopsies were taken to confirm the definitive diagnosis, and endoscopic debulking of mass was performed to provide symptomatic relief. Patient was free from nasal symptoms, and residual nasal and nasopharyngeal masses showed no increment in size and number during follow-up. Conclusion Xanthogranulomatous inflammation in the nasal cavity and nasopharynx can be easily confused with other nasal masses. A histopathology examination is crucial to establish the diagnosis. A repeated biopsy is needed if previous biopsy result is inconclusive. Surgical excision is recommended for symptomatic relief. The effectiveness of medical treatment is still unclear. A long-term follow-up is mandatory.
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spelling doaj.art-a794ff451a46460abb20e6df9549bc072024-04-16T12:12:50ZengSpringerOpenThe Egyptian Journal of Otolaryngology1012-55742090-85392022-01-013811510.1186/s43163-022-00201-5Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case reportWei Jie Boon0Khim Soon Vong1Ing Ping Tang2Department of ORL HNS, Sarawak General HospitalDepartment of ORL HNS, Sarawak General HospitalDepartment of ORL HNS, Sarawak General HospitalAbstract Background Xanthogranulomatous inflammation is an uncommon condition in adult nasal cavity and nasopharynx. Case presentation We report a male patient who developed xanthogranulomatous inflammation in the bilateral nose and nasopharynx. The patient was not responsive to oral steroid. Multiple biopsies were taken to confirm the definitive diagnosis, and endoscopic debulking of mass was performed to provide symptomatic relief. Patient was free from nasal symptoms, and residual nasal and nasopharyngeal masses showed no increment in size and number during follow-up. Conclusion Xanthogranulomatous inflammation in the nasal cavity and nasopharynx can be easily confused with other nasal masses. A histopathology examination is crucial to establish the diagnosis. A repeated biopsy is needed if previous biopsy result is inconclusive. Surgical excision is recommended for symptomatic relief. The effectiveness of medical treatment is still unclear. A long-term follow-up is mandatory.https://doi.org/10.1186/s43163-022-00201-5Xanthogranulomatous inflammationNasal cavity massNasopharynx mass
spellingShingle Wei Jie Boon
Khim Soon Vong
Ing Ping Tang
Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
The Egyptian Journal of Otolaryngology
Xanthogranulomatous inflammation
Nasal cavity mass
Nasopharynx mass
title Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
title_full Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
title_fullStr Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
title_full_unstemmed Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
title_short Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report
title_sort bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass a case report
topic Xanthogranulomatous inflammation
Nasal cavity mass
Nasopharynx mass
url https://doi.org/10.1186/s43163-022-00201-5
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