Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia
Respected Editor, Beta thalassaemia is an autosomal recessive disorder that leads to abnormal production of functional adult haemoglobin because of either inadequate or absent production of the B globin chain (beta+/beta0).1 Transfusion-dependent thalassemia (TDT) is a rare and most severe form req...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2023-09-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://ojs.jpma.org.pk/index.php/public_html/article/view/9532 |
| _version_ | 1797685251556769792 |
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| author | Hiba Tariq Wally Muhammad Hassan Zulfi Elahi Sana Jilani |
| author_facet | Hiba Tariq Wally Muhammad Hassan Zulfi Elahi Sana Jilani |
| author_sort | Hiba Tariq Wally |
| collection | DOAJ |
| description |
Respected Editor, Beta thalassaemia is an autosomal recessive disorder that leads to abnormal production of functional adult haemoglobin because of either inadequate or absent production of the B globin chain (beta+/beta0).1 Transfusion-dependent thalassemia (TDT) is a rare and most severe form requiring life-long blood transfusions. To mitigate the effects of TDT, life-long blood transfusions every 2-5 weeks are required, which can elicit transfusion-based reactions and lead to an iron overload state, which can further cause widespread organ damage despite the use of iron chelation therapy.2
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| first_indexed | 2024-03-12T00:41:28Z |
| format | Article |
| id | doaj.art-a79577966e4d433ea2cc75fe39d79980 |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-03-12T00:41:28Z |
| publishDate | 2023-09-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-a79577966e4d433ea2cc75fe39d799802023-09-15T04:52:50ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822023-09-01731010.47391/JPMA.9532Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemiaHiba Tariq Wally0Muhammad Hassan Zulfi1Elahi Sana Jilani2Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, PakistanDepartment of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, PakistanDepartment of Orthopaedic Surgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan Respected Editor, Beta thalassaemia is an autosomal recessive disorder that leads to abnormal production of functional adult haemoglobin because of either inadequate or absent production of the B globin chain (beta+/beta0).1 Transfusion-dependent thalassemia (TDT) is a rare and most severe form requiring life-long blood transfusions. To mitigate the effects of TDT, life-long blood transfusions every 2-5 weeks are required, which can elicit transfusion-based reactions and lead to an iron overload state, which can further cause widespread organ damage despite the use of iron chelation therapy.2 Continue... https://ojs.jpma.org.pk/index.php/public_html/article/view/9532 |
| spellingShingle | Hiba Tariq Wally Muhammad Hassan Zulfi Elahi Sana Jilani Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia Journal of the Pakistan Medical Association |
| title | Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia |
| title_full | Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia |
| title_fullStr | Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia |
| title_full_unstemmed | Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia |
| title_short | Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia |
| title_sort | betibeglogene autotemcel a new hope for transfusion dependent beta thalassaemia |
| url | https://ojs.jpma.org.pk/index.php/public_html/article/view/9532 |
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