Transcriptomic and ChIP-seq Integrative Analysis Identifies KDM5A-Target Genes in Cardiac Fibroblasts

Transcriptomic and ChIP-seq Integrative Analysis Identifies KDM5A-Target Genes in Cardiac Fibroblasts

Cardiac fibrosis is a common pathological feature in cardiac remodeling. This study aimed to explore the role of KDM5A in cardiac fibrosis via bioinformatics analysis. Cardiac fibroblasts (CFs) were harvested and cultured from 10 dilated cardiomyopathy (DCM) patients who underwent heart transplantat...

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Bibliographic Details
Main Authors: Yiyao Jiang, Xu Zhang, Ting Wei, Xianjie Qi, Isah Amir Abba, Nana Zhang, Yao Chen, Ran Wang, Chao Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
KDM5A
cardiac fibrosis
differentially expressed genes
integrative bioinformatics analysis
cardiac fibroblasts
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.929030/full

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