Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors
Cord blood cell composition is a short-lasting delivery stress consequence and is similar on adult G-CSF-mobilized peripheral blood.G-CSF realizes biological effect by number of secondary messengers, many of which are also natural effectors of stress. In this research comparative characteristics of...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2022-11-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/785 |
| _version_ | 1797855492019585024 |
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| author | R. Sh. Ibragimov E. V. Raikina E. Yu. Osipova N. N. Zimina O. A. Maiorova M. V. Yakovleva S. A. Roumiantsev |
| author_facet | R. Sh. Ibragimov E. V. Raikina E. Yu. Osipova N. N. Zimina O. A. Maiorova M. V. Yakovleva S. A. Roumiantsev |
| author_sort | R. Sh. Ibragimov |
| collection | DOAJ |
| description | Cord blood cell composition is a short-lasting delivery stress consequence and is similar on adult G-CSF-mobilized peripheral blood.G-CSF realizes biological effect by number of secondary messengers, many of which are also natural effectors of stress. In this research comparative characteristics of cell composition, including lymphocytes subpopulations, CD34+ and CD133+ cells, hematopoietic progenitor cells colony-forming activity and mobilizing cytokines concentration (IL-8, MMP-2, MMP-9), between term newborns cord blood and G-CSF-mobilized peripheral blood is shown.Mobilized cytokines concentration ratio in combination with CD34+ cells count in cord blood and mobilized peripheral blood suggests that delivery stress possibly is not single cause of cord blood features. |
| first_indexed | 2024-04-09T20:23:21Z |
| format | Article |
| id | doaj.art-a79a17ea97b442ecb6871d6ccbce6cc7 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:23:21Z |
| publishDate | 2022-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-a79a17ea97b442ecb6871d6ccbce6cc72023-03-30T20:15:16ZrusABV-pressОнкогематология1818-83462413-40232022-11-0104455010.17650/1818-8346-2009-0-4-45-50663Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donorsR. Sh. Ibragimov0E. V. Raikina1E. Yu. Osipova2N. N. Zimina3O. A. Maiorova4M. V. Yakovleva5S. A. Roumiantsev6Federal research center of pediatric hematology, oncology and immunologyFederal research center of pediatric hematology, oncology and immunology; Moscow Stem cells bankFederal research center of pediatric hematology, oncology and immunology; Moscow Stem cells bankMoscow Center of family planning and reproductionFederal research center of pediatric hematology, oncology and immunologyMoscow Stem cells bankFederal research center of pediatric hematology, oncology and immunology; Moscow Stem cells bankCord blood cell composition is a short-lasting delivery stress consequence and is similar on adult G-CSF-mobilized peripheral blood.G-CSF realizes biological effect by number of secondary messengers, many of which are also natural effectors of stress. In this research comparative characteristics of cell composition, including lymphocytes subpopulations, CD34+ and CD133+ cells, hematopoietic progenitor cells colony-forming activity and mobilizing cytokines concentration (IL-8, MMP-2, MMP-9), between term newborns cord blood and G-CSF-mobilized peripheral blood is shown.Mobilized cytokines concentration ratio in combination with CD34+ cells count in cord blood and mobilized peripheral blood suggests that delivery stress possibly is not single cause of cord blood features.https://oncohematology.abvpress.ru/ongm/article/view/785cord bloodmobilizationcd34+ cellscd133+ cellsgranulocyte colony stimulated factor |
| spellingShingle | R. Sh. Ibragimov E. V. Raikina E. Yu. Osipova N. N. Zimina O. A. Maiorova M. V. Yakovleva S. A. Roumiantsev Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors Онкогематология cord blood mobilization cd34+ cells cd133+ cells granulocyte colony stimulated factor |
| title | Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors |
| title_full | Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors |
| title_fullStr | Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors |
| title_full_unstemmed | Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors |
| title_short | Comparative characteristics of healthy newborns cord blood cell composition and G-SCF-mobilized blood from healthy donors |
| title_sort | comparative characteristics of healthy newborns cord blood cell composition and g scf mobilized blood from healthy donors |
| topic | cord blood mobilization cd34+ cells cd133+ cells granulocyte colony stimulated factor |
| url | https://oncohematology.abvpress.ru/ongm/article/view/785 |
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