Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distille...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2013-03-01
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| Series: | Acta Cirúrgica Brasileira |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005 |
| _version_ | 1819289080885673984 |
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| author | Nara Macedo Botelho Suelen Costa Corrêa Rodolfo Costa Lobato Renan Kleber Costa Teixeira Juarez Antônio Simões Quaresma |
| author_facet | Nara Macedo Botelho Suelen Costa Corrêa Rodolfo Costa Lobato Renan Kleber Costa Teixeira Juarez Antônio Simões Quaresma |
| author_sort | Nara Macedo Botelho |
| collection | DOAJ |
| description | PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor. |
| first_indexed | 2024-12-24T03:01:10Z |
| format | Article |
| id | doaj.art-a79c7edf65eb4af2b27a40442690dde5 |
| institution | Directory Open Access Journal |
| issn | 0102-8650 1678-2674 |
| language | English |
| last_indexed | 2024-12-24T03:01:10Z |
| publishDate | 2013-03-01 |
| publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| record_format | Article |
| series | Acta Cirúrgica Brasileira |
| spelling | doaj.art-a79c7edf65eb4af2b27a40442690dde52022-12-21T17:18:13ZengSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira0102-86501678-26742013-03-01283185189Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsamNara Macedo BotelhoSuelen Costa CorrêaRodolfo Costa LobatoRenan Kleber Costa TeixeiraJuarez Antônio Simões QuaresmaPURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005Carcinoma 256, WalkerImmunohistochemistryCervix UteriRats |
| spellingShingle | Nara Macedo Botelho Suelen Costa Corrêa Rodolfo Costa Lobato Renan Kleber Costa Teixeira Juarez Antônio Simões Quaresma Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam Acta Cirúrgica Brasileira Carcinoma 256, Walker Immunohistochemistry Cervix Uteri Rats |
| title | Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam |
| title_full | Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam |
| title_fullStr | Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam |
| title_full_unstemmed | Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam |
| title_short | Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam |
| title_sort | immunohistochemistry of the uterine cervix of rats bearing the walker 256 tumor treated with copaiba balsam |
| topic | Carcinoma 256, Walker Immunohistochemistry Cervix Uteri Rats |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005 |
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