Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

(1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and important therapeutic challenge due to the lifelong need for exogeneous insulin administration. Early metabolic biomarkers...

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Bibliographic Details
Main Authors: Oscar Alcazar, Luis F. Hernandez, Ashley Tschiggfrie, Michael J. Muehlbauer, James R. Bain, Peter Buchwald, Midhat H. Abdulreda
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Metabolites
Subjects:
autoimmune diabetes
anterior chamber of the eye
gender differences
non-obese diabetic (nod) mice
pancreatic islet
local metabolomics
non-targeted metabolomics
gc-ms
islet microenvironment
t1d biomarkers
Online Access:https://www.mdpi.com/2218-1989/9/10/207

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https://www.mdpi.com/2218-1989/9/10/207

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