Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis
Abstract Background Our study compares the outcomes of extensive spinal metastasis patients treated with Ultra-Long Construct Navigated Minimally Invasive Spine Surgery (UNMISS) with Adjuvant Radiotherapy to those receiving only radiotherapy. Spinal metastasis often necessitates interventions like r...
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-023-11729-x |
| _version_ | 1797376927035555840 |
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| author | Borriwat Santipas Monchai Ruangchainikom Sirichai Wilartratsami Supachat Jiamamornrat Nhathita Panatreswas Panya Luksanapruksa |
| author_facet | Borriwat Santipas Monchai Ruangchainikom Sirichai Wilartratsami Supachat Jiamamornrat Nhathita Panatreswas Panya Luksanapruksa |
| author_sort | Borriwat Santipas |
| collection | DOAJ |
| description | Abstract Background Our study compares the outcomes of extensive spinal metastasis patients treated with Ultra-Long Construct Navigated Minimally Invasive Spine Surgery (UNMISS) with Adjuvant Radiotherapy to those receiving only radiotherapy. Spinal metastasis often necessitates interventions like radiotherapy, chemotherapy, or surgery, with an increasing trend towards surgical management. minimally invasive spine surgery has demonstrated advantages over traditional open surgery, with fewer complications and better postoperative outcomes. Radiotherapy continues as a standard for those unsuitable for surgery. Methods This retrospective study included extensive spinal metastasis patients treated between January 2017 and December 2020. We compared patients undergoing UNMISS in conjunction with radiotherapy to patients receiving radiotherapy alone, evaluating demographic data, disease characteristics, and treatment outcomes (VAS, survival) to establish statistical significance. Results Twenty-three patients were included in our study. Fourteen patients underwent UNMISS, and nine patients received radiotherapy alone. There was no difference in baseline characteristics of patients. The longest construct in our case series involved T1 to iliac. Both cohorts showed significant improvement in pain scores post-treatment (p = 0.01). However, the UNMISS group demonstrated significantly lower post-treatment VAS scores (p = 0.003), indicating enhanced pain relief. Survival outcomes did not differ significantly between the two groups. Conclusion The UNMISS should be considered as an alternative treatment in a patient with symptomatic extensive spinal metastasis. The primary goal of this technique is to stabilize the multiple levels of spinal metastasis and decompression of the neural element if needed. This technique is safe and has a better outcome in pain improvement than the patient who received radiotherapy alone. |
| first_indexed | 2024-03-08T19:46:35Z |
| format | Article |
| id | doaj.art-a79e92abc1734933afb8c9f7b4b69cb6 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-03-08T19:46:35Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-a79e92abc1734933afb8c9f7b4b69cb62023-12-24T12:21:44ZengBMCBMC Cancer1471-24072023-12-012311910.1186/s12885-023-11729-xSafety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysisBorriwat Santipas0Monchai Ruangchainikom1Sirichai Wilartratsami2Supachat Jiamamornrat3Nhathita Panatreswas4Panya Luksanapruksa5Division of Spine Surgery, Department of Orthopedic Surgery, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDivision of Spine Surgery, Department of Orthopedic Surgery, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDivision of Spine Surgery, Department of Orthopedic Surgery, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDivision of Spine Surgery, Department of Orthopedic Surgery, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityResearch unit, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDivision of Spine Surgery, Department of Orthopedic Surgery, Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol UniversityAbstract Background Our study compares the outcomes of extensive spinal metastasis patients treated with Ultra-Long Construct Navigated Minimally Invasive Spine Surgery (UNMISS) with Adjuvant Radiotherapy to those receiving only radiotherapy. Spinal metastasis often necessitates interventions like radiotherapy, chemotherapy, or surgery, with an increasing trend towards surgical management. minimally invasive spine surgery has demonstrated advantages over traditional open surgery, with fewer complications and better postoperative outcomes. Radiotherapy continues as a standard for those unsuitable for surgery. Methods This retrospective study included extensive spinal metastasis patients treated between January 2017 and December 2020. We compared patients undergoing UNMISS in conjunction with radiotherapy to patients receiving radiotherapy alone, evaluating demographic data, disease characteristics, and treatment outcomes (VAS, survival) to establish statistical significance. Results Twenty-three patients were included in our study. Fourteen patients underwent UNMISS, and nine patients received radiotherapy alone. There was no difference in baseline characteristics of patients. The longest construct in our case series involved T1 to iliac. Both cohorts showed significant improvement in pain scores post-treatment (p = 0.01). However, the UNMISS group demonstrated significantly lower post-treatment VAS scores (p = 0.003), indicating enhanced pain relief. Survival outcomes did not differ significantly between the two groups. Conclusion The UNMISS should be considered as an alternative treatment in a patient with symptomatic extensive spinal metastasis. The primary goal of this technique is to stabilize the multiple levels of spinal metastasis and decompression of the neural element if needed. This technique is safe and has a better outcome in pain improvement than the patient who received radiotherapy alone.https://doi.org/10.1186/s12885-023-11729-xUltralong constructionMinimally invasive spine surgeryRadiotherapyMultiple spinal metastasisExtensive spinal metastasis |
| spellingShingle | Borriwat Santipas Monchai Ruangchainikom Sirichai Wilartratsami Supachat Jiamamornrat Nhathita Panatreswas Panya Luksanapruksa Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis BMC Cancer Ultralong construction Minimally invasive spine surgery Radiotherapy Multiple spinal metastasis Extensive spinal metastasis |
| title | Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis |
| title_full | Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis |
| title_fullStr | Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis |
| title_full_unstemmed | Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis |
| title_short | Safety and feasibility of ultra-long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis : a comparative analysis |
| title_sort | safety and feasibility of ultra long construct navigated minimally invasive spine surgery with adjuvant radiotherapy in extensive spinal metastasis a comparative analysis |
| topic | Ultralong construction Minimally invasive spine surgery Radiotherapy Multiple spinal metastasis Extensive spinal metastasis |
| url | https://doi.org/10.1186/s12885-023-11729-x |
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