Differential Modulation of the Phospholipidome of Proinflammatory Human Macrophages by the Flavonoids Quercetin, Naringin and Naringenin

Differential Modulation of the Phospholipidome of Proinflammatory Human Macrophages by the Flavonoids Quercetin, Naringin and Naringenin

The immunomodulatory activity of flavonoids is increasingly appreciated. Macrophage phospholipids (PLs) play crucial roles in cell-mediated inflammatory responses. However, little is known on how these PLs are affected upon flavonoid treatment. In this work, we have used mass-spectrometry-based lipi...

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Bibliographic Details
Main Authors: Tiago A. Conde, Luís Mendes, Vítor M. Gaspar, João F. Mano, Tânia Melo, M. Rosário Domingues, Iola F. Duarte
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
macrophages
phospholipids
flavonoids
immunomodulation
inflammation
lipidomics
Online Access:https://www.mdpi.com/1420-3049/25/15/3460

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