Natural and Engineered Sex Ratio Distortion in Insects
Insects have evolved highly diverse genetic sex-determination mechanisms and a relatively balanced male to female sex ratio is generally expected. However, selection may shift the optimal sex ratio while meiotic drive and endosymbiont manipulation can result in sex ratio distortion (SRD). Recent adv...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Ecology and Evolution |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fevo.2022.884159/full |
| _version_ | 1818204026374717440 |
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| author | Austin Compton Austin Compton Zhijian Tu Zhijian Tu |
| author_facet | Austin Compton Austin Compton Zhijian Tu Zhijian Tu |
| author_sort | Austin Compton |
| collection | DOAJ |
| description | Insects have evolved highly diverse genetic sex-determination mechanisms and a relatively balanced male to female sex ratio is generally expected. However, selection may shift the optimal sex ratio while meiotic drive and endosymbiont manipulation can result in sex ratio distortion (SRD). Recent advances in sex chromosome genomics and CRISPR/Cas9-mediated genome editing brought significant insights into the molecular regulators of sex determination in an increasing number of insects and provided new ways to engineer SRD. We review these advances and discuss both naturally occurring and engineered SRD in the context of the Anthropocene. We emphasize SRD-mediated biological control of insects to help improve One Health, sustain agriculture, and conserve endangered species. |
| first_indexed | 2024-12-12T03:34:41Z |
| format | Article |
| id | doaj.art-a79faa7819094f008bc126c3d9482b14 |
| institution | Directory Open Access Journal |
| issn | 2296-701X |
| language | English |
| last_indexed | 2024-12-12T03:34:41Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Ecology and Evolution |
| spelling | doaj.art-a79faa7819094f008bc126c3d9482b142022-12-22T00:39:50ZengFrontiers Media S.A.Frontiers in Ecology and Evolution2296-701X2022-06-011010.3389/fevo.2022.884159884159Natural and Engineered Sex Ratio Distortion in InsectsAustin Compton0Austin Compton1Zhijian Tu2Zhijian Tu3Department of Biochemistry, Virginia Tech, Blacksburg, VA, United StatesFralin Life Sciences Institute, Virginia Tech, Blacksburg, VA, United StatesDepartment of Biochemistry, Virginia Tech, Blacksburg, VA, United StatesFralin Life Sciences Institute, Virginia Tech, Blacksburg, VA, United StatesInsects have evolved highly diverse genetic sex-determination mechanisms and a relatively balanced male to female sex ratio is generally expected. However, selection may shift the optimal sex ratio while meiotic drive and endosymbiont manipulation can result in sex ratio distortion (SRD). Recent advances in sex chromosome genomics and CRISPR/Cas9-mediated genome editing brought significant insights into the molecular regulators of sex determination in an increasing number of insects and provided new ways to engineer SRD. We review these advances and discuss both naturally occurring and engineered SRD in the context of the Anthropocene. We emphasize SRD-mediated biological control of insects to help improve One Health, sustain agriculture, and conserve endangered species.https://www.frontiersin.org/articles/10.3389/fevo.2022.884159/fullCRISPR/Cas9sex chromosomesex-determinationgene driveendosymbiont bacteriaclimate change |
| spellingShingle | Austin Compton Austin Compton Zhijian Tu Zhijian Tu Natural and Engineered Sex Ratio Distortion in Insects Frontiers in Ecology and Evolution CRISPR/Cas9 sex chromosome sex-determination gene drive endosymbiont bacteria climate change |
| title | Natural and Engineered Sex Ratio Distortion in Insects |
| title_full | Natural and Engineered Sex Ratio Distortion in Insects |
| title_fullStr | Natural and Engineered Sex Ratio Distortion in Insects |
| title_full_unstemmed | Natural and Engineered Sex Ratio Distortion in Insects |
| title_short | Natural and Engineered Sex Ratio Distortion in Insects |
| title_sort | natural and engineered sex ratio distortion in insects |
| topic | CRISPR/Cas9 sex chromosome sex-determination gene drive endosymbiont bacteria climate change |
| url | https://www.frontiersin.org/articles/10.3389/fevo.2022.884159/full |
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