Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology

Purpose: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of A...

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Main Authors: Boon Lin Teh, Paul Y S Chua, Aravind R Reddy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=9;spage=2437;epage=2440;aulast=Teh
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author Boon Lin Teh
Paul Y S Chua
Aravind R Reddy
author_facet Boon Lin Teh
Paul Y S Chua
Aravind R Reddy
author_sort Boon Lin Teh
collection DOAJ
description Purpose: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of ADCE for RCE of traumatic etiology. Methods: This is a retrospective review of consecutive patients who underwent ADCE for traumatic RCE in a local hospital between January 2010 and January 2020. The outcomes at a 3-year follow-up review are included. Nonsurgical therapy used; intra- and postoperative complications were recorded. ADCE was only offered to those who remained symptomatic despite maximum topical lubrications and/or extended wear contact lens. Success was defined as the absence of recurrence of corneal erosion. Results: Twenty-six eyes of 26 patients with RCE caused by trauma underwent ADCE. The mean age of patients was 39 years. The follow-up period was a minimum of 36 months. Three eyes (11.5%) had recurrence of corneal erosion after ADCE at the 3-year follow-up. Recurrence was noted at months 2, 23, and 36 postoperatively in these patients. All patients reported significant improvement in symptoms associated with recurrent erosion. Ten eyes (38.5%) stopped all topical lubricants postoperatively. No intra- or postoperative complications were noted in our study. Conclusion: This study documents the long-term safety and efficacy of alcohol delamination of corneal epithelium at 3 years for patients with RCE of traumatic origin.
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spelling doaj.art-a7a5cfacb332432c95f357817bbad8a82022-12-21T21:27:01ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892021-01-016992437244010.4103/ijo.IJO_3796_20Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiologyBoon Lin TehPaul Y S ChuaAravind R ReddyPurpose: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of ADCE for RCE of traumatic etiology. Methods: This is a retrospective review of consecutive patients who underwent ADCE for traumatic RCE in a local hospital between January 2010 and January 2020. The outcomes at a 3-year follow-up review are included. Nonsurgical therapy used; intra- and postoperative complications were recorded. ADCE was only offered to those who remained symptomatic despite maximum topical lubrications and/or extended wear contact lens. Success was defined as the absence of recurrence of corneal erosion. Results: Twenty-six eyes of 26 patients with RCE caused by trauma underwent ADCE. The mean age of patients was 39 years. The follow-up period was a minimum of 36 months. Three eyes (11.5%) had recurrence of corneal erosion after ADCE at the 3-year follow-up. Recurrence was noted at months 2, 23, and 36 postoperatively in these patients. All patients reported significant improvement in symptoms associated with recurrent erosion. Ten eyes (38.5%) stopped all topical lubricants postoperatively. No intra- or postoperative complications were noted in our study. Conclusion: This study documents the long-term safety and efficacy of alcohol delamination of corneal epithelium at 3 years for patients with RCE of traumatic origin.http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=9;spage=2437;epage=2440;aulast=Tehalcohol delaminationefficacytraumatic recurrent corneal erosions
spellingShingle Boon Lin Teh
Paul Y S Chua
Aravind R Reddy
Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
Indian Journal of Ophthalmology
alcohol delamination
efficacy
traumatic recurrent corneal erosions
title Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_full Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_fullStr Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_full_unstemmed Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_short Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_sort three year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
topic alcohol delamination
efficacy
traumatic recurrent corneal erosions
url http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=9;spage=2437;epage=2440;aulast=Teh
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AT paulyschua threeyearoutcomesofalcoholdelaminationofcornealepitheliumforrecurrentcornealerosionsoftraumaticetiology
AT aravindrreddy threeyearoutcomesofalcoholdelaminationofcornealepitheliumforrecurrentcornealerosionsoftraumaticetiology