Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study
Anna Maria Comberiati,1 Chiara Lomartire,1 Mariaelena Malvasi,1 Raffaele Migliorini,1 Fernanda Pacella,2 Vito Maurizio Malvasi,3 Paolo Turchetti,4 Elena Pacella1 1Department of Sense Organs, Sapienza University of Rome, Rome, Italy; 2Department of Ophthalmology, Carlo Poma Hospital, Mantua, Italy; 3...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2024-02-01
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| Series: | Clinical Optometry |
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| Online Access: | https://www.dovepress.com/alteration-ocular-motility-in-retinitis-pigmentosa-casecontrol-study-peer-reviewed-fulltext-article-OPTO |
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| author | Comberiati AM Lomartire C Malvasi M Migliorini R Pacella F Malvasi VM Turchetti P Pacella E |
| author_facet | Comberiati AM Lomartire C Malvasi M Migliorini R Pacella F Malvasi VM Turchetti P Pacella E |
| author_sort | Comberiati AM |
| collection | DOAJ |
| description | Anna Maria Comberiati,1 Chiara Lomartire,1 Mariaelena Malvasi,1 Raffaele Migliorini,1 Fernanda Pacella,2 Vito Maurizio Malvasi,3 Paolo Turchetti,4 Elena Pacella1 1Department of Sense Organs, Sapienza University of Rome, Rome, Italy; 2Department of Ophthalmology, Carlo Poma Hospital, Mantua, Italy; 3Department of Odontostomatological and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy; 4National Institute for Health, Migration and Poverty (INMP/NIHMP), Rome, ItalyCorrespondence: Mariaelena Malvasi, Department of Sense Organs, University of Rome, “Sapienza” via Del Policlinico 155, Rome, 00161, Italy, Tel +393402114859, Email mariaelena.malvasi@uniroma1.itPurpose: To evaluate ocular motility (OM) disorders and strabismus in a sample of patients with retinitis pigmentosa (RP) and a control sample.Methods: In this cross-sectional retrospective analysis, we studied a sample of RP patients with a mean age of 48.74 years and an average visual acuity of 7/10 based on Snellen optotype and a sample of control patients with similar mean age (49 years [men], 47 years [women]) and sex and an average visual acuity of 9.9/10, with the aim of assessing correlations between alteration of OM and strabismus in RP patients based on age, high refractive defect, or severely impaired binocular vision. The examination followed a protocol of testing for anamnesis and best-corrected visual acuity, as well as a complete eye examination, corneal reflex, cover test, OM, Hess screen, and Lang test.Results: At the first orthoptic evaluation, 45.16% of patients showed strabismus, 41.93% exotropia (25% of cases intermittent), 3.22% esotropia, and 6.45% vertical deviation. Later evaluation showed strabismus in 25.80% of patients, exotropia in 19.35% (9.67% intermittent), esotropia in 3.22%, and vertical deviation in 3.22%. Assessment of eye motility study showed 51.6% overaction of the inferior oblique and hypofunction of the superior rectus, and 18% overaction of the lateral rectus and hypofunction of the medial rectus. According to our results, alterations in OM and strabismus in RP patients are not correlated with age or high refractive defect. Therefore, motility disorders and strabismus are attributed to a genetic factor to which men are more susceptible.Conclusion: The incidence of OM disorder was 77.42%, and strabismus was present in 45.16% of patients.Keywords: retinitis pigmentosa, orthoptic evaluation, strabismus, genetic factor, ocular motility |
| first_indexed | 2024-03-07T22:58:29Z |
| format | Article |
| id | doaj.art-a7a68785e9b747c4b30110c3c5ec54f7 |
| institution | Directory Open Access Journal |
| issn | 1179-2752 |
| language | English |
| last_indexed | 2024-03-07T22:58:29Z |
| publishDate | 2024-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Optometry |
| spelling | doaj.art-a7a68785e9b747c4b30110c3c5ec54f72024-02-22T18:28:24ZengDove Medical PressClinical Optometry1179-27522024-02-01Volume 16556990623Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control StudyComberiati AMLomartire CMalvasi MMigliorini RPacella FMalvasi VMTurchetti PPacella EAnna Maria Comberiati,1 Chiara Lomartire,1 Mariaelena Malvasi,1 Raffaele Migliorini,1 Fernanda Pacella,2 Vito Maurizio Malvasi,3 Paolo Turchetti,4 Elena Pacella1 1Department of Sense Organs, Sapienza University of Rome, Rome, Italy; 2Department of Ophthalmology, Carlo Poma Hospital, Mantua, Italy; 3Department of Odontostomatological and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy; 4National Institute for Health, Migration and Poverty (INMP/NIHMP), Rome, ItalyCorrespondence: Mariaelena Malvasi, Department of Sense Organs, University of Rome, “Sapienza” via Del Policlinico 155, Rome, 00161, Italy, Tel +393402114859, Email mariaelena.malvasi@uniroma1.itPurpose: To evaluate ocular motility (OM) disorders and strabismus in a sample of patients with retinitis pigmentosa (RP) and a control sample.Methods: In this cross-sectional retrospective analysis, we studied a sample of RP patients with a mean age of 48.74 years and an average visual acuity of 7/10 based on Snellen optotype and a sample of control patients with similar mean age (49 years [men], 47 years [women]) and sex and an average visual acuity of 9.9/10, with the aim of assessing correlations between alteration of OM and strabismus in RP patients based on age, high refractive defect, or severely impaired binocular vision. The examination followed a protocol of testing for anamnesis and best-corrected visual acuity, as well as a complete eye examination, corneal reflex, cover test, OM, Hess screen, and Lang test.Results: At the first orthoptic evaluation, 45.16% of patients showed strabismus, 41.93% exotropia (25% of cases intermittent), 3.22% esotropia, and 6.45% vertical deviation. Later evaluation showed strabismus in 25.80% of patients, exotropia in 19.35% (9.67% intermittent), esotropia in 3.22%, and vertical deviation in 3.22%. Assessment of eye motility study showed 51.6% overaction of the inferior oblique and hypofunction of the superior rectus, and 18% overaction of the lateral rectus and hypofunction of the medial rectus. According to our results, alterations in OM and strabismus in RP patients are not correlated with age or high refractive defect. Therefore, motility disorders and strabismus are attributed to a genetic factor to which men are more susceptible.Conclusion: The incidence of OM disorder was 77.42%, and strabismus was present in 45.16% of patients.Keywords: retinitis pigmentosa, orthoptic evaluation, strabismus, genetic factor, ocular motilityhttps://www.dovepress.com/alteration-ocular-motility-in-retinitis-pigmentosa-casecontrol-study-peer-reviewed-fulltext-article-OPTOretinits pigmentosaorthoptic evaluationstrabismusgenetic factor. |
| spellingShingle | Comberiati AM Lomartire C Malvasi M Migliorini R Pacella F Malvasi VM Turchetti P Pacella E Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study Clinical Optometry retinits pigmentosa orthoptic evaluation strabismus genetic factor. |
| title | Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study |
| title_full | Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study |
| title_fullStr | Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study |
| title_full_unstemmed | Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study |
| title_short | Alteration Ocular Motility in Retinitis Pigmentosa: Case–Control Study |
| title_sort | alteration ocular motility in retinitis pigmentosa case ndash control study |
| topic | retinits pigmentosa orthoptic evaluation strabismus genetic factor. |
| url | https://www.dovepress.com/alteration-ocular-motility-in-retinitis-pigmentosa-casecontrol-study-peer-reviewed-fulltext-article-OPTO |
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