MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS

АТМ Asp1853Asn, Lig4 Ala3Val, and NBS Glu185Gln genes polymorphism in two ethnic groups of Kemerovo region (the Shors and the Russians) has been studied. The frequency of minor АТМ1853Asn allele in the Shors group corresponds to the data obtained for Mongoloids (in various world populations) and is...

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Bibliographic Details
Main Authors: V. I. Minina, V. G. Druzhinin, A. A. Timofeeva, A. V. Ryzhkova, A. V. Larionov
Format: Article
Language:English
Published: Kemerovo State University 2013-06-01
Series:Вестник Кемеровского государственного университета
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Online Access:https://vestnik.kemsu.ru/jour/article/view/63
Description
Summary:АТМ Asp1853Asn, Lig4 Ala3Val, and NBS Glu185Gln genes polymorphism in two ethnic groups of Kemerovo region (the Shors and the Russians) has been studied. The frequency of minor АТМ1853Asn allele in the Shors group corresponds to the data obtained for Mongoloids (in various world populations) and is significantly lower than the inci dence of this allele in the Russians in Kemerovo region. The frequencies of Lig4¸ NBS1 alleles and genotypes in the. Russians and the Shors do not differ, as stated in the previous research. These data indicates a big share of the Mongolo id component in the genome of the indigenous people of Siberia – the Shors.
ISSN:2078-8975
2078-8983