MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS

АТМ Asp1853Asn, Lig4 Ala3Val, and NBS Glu185Gln genes polymorphism in two ethnic groups of Kemerovo region (the Shors and the Russians) has been studied. The frequency of minor АТМ1853Asn allele in the Shors group corresponds to the data obtained for Mongoloids (in various world populations) and is...

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Main Authors: V. I. Minina, V. G. Druzhinin, A. A. Timofeeva, A. V. Ryzhkova, A. V. Larionov
Format: Article
Language:English
Published: Kemerovo State University 2013-06-01
Series:Вестник Кемеровского государственного университета
Subjects:
Online Access:https://vestnik.kemsu.ru/jour/article/view/63
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author V. I. Minina
V. G. Druzhinin
A. A. Timofeeva
A. V. Ryzhkova
A. V. Larionov
author_facet V. I. Minina
V. G. Druzhinin
A. A. Timofeeva
A. V. Ryzhkova
A. V. Larionov
author_sort V. I. Minina
collection DOAJ
description АТМ Asp1853Asn, Lig4 Ala3Val, and NBS Glu185Gln genes polymorphism in two ethnic groups of Kemerovo region (the Shors and the Russians) has been studied. The frequency of minor АТМ1853Asn allele in the Shors group corresponds to the data obtained for Mongoloids (in various world populations) and is significantly lower than the inci dence of this allele in the Russians in Kemerovo region. The frequencies of Lig4¸ NBS1 alleles and genotypes in the. Russians and the Shors do not differ, as stated in the previous research. These data indicates a big share of the Mongolo id component in the genome of the indigenous people of Siberia – the Shors.
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spelling doaj.art-a7a6fe83f5024dddbb7dbf5f96ffe2132023-07-13T12:08:27ZengKemerovo State UniversityВестник Кемеровского государственного университета2078-89752078-89832013-06-0102-1212563MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONSV. I. Minina0V. G. Druzhinin1A. A. Timofeeva2A. V. Ryzhkova3A. V. Larionov4Kemerovo State University; Institute for Human Ecology of the Siberian branch of the RASKemerovo State University; Institute for Human Ecology of the Siberian branch of the RASKemerovo State University; Institute for Human Ecology of the Siberian branch of the RASKemerovo State UniversityKemerovo State UniversityАТМ Asp1853Asn, Lig4 Ala3Val, and NBS Glu185Gln genes polymorphism in two ethnic groups of Kemerovo region (the Shors and the Russians) has been studied. The frequency of minor АТМ1853Asn allele in the Shors group corresponds to the data obtained for Mongoloids (in various world populations) and is significantly lower than the inci dence of this allele in the Russians in Kemerovo region. The frequencies of Lig4¸ NBS1 alleles and genotypes in the. Russians and the Shors do not differ, as stated in the previous research. These data indicates a big share of the Mongolo id component in the genome of the indigenous people of Siberia – the Shors.https://vestnik.kemsu.ru/jour/article/view/63atmlig4nbs1 gene polymorphism
spellingShingle V. I. Minina
V. G. Druzhinin
A. A. Timofeeva
A. V. Ryzhkova
A. V. Larionov
MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
Вестник Кемеровского государственного университета
atm
lig4
nbs1 gene polymorphism
title MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
title_full MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
title_fullStr MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
title_full_unstemmed MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
title_short MOLECULAR GENETIC ANALYSIS OF DOUBLE-STRAND DNA BREAK REPAIR GENES POLYMORPHISM IN INDIGENOUS AND MIGRANT POPULATIONS
title_sort molecular genetic analysis of double strand dna break repair genes polymorphism in indigenous and migrant populations
topic atm
lig4
nbs1 gene polymorphism
url https://vestnik.kemsu.ru/jour/article/view/63
work_keys_str_mv AT viminina moleculargeneticanalysisofdoublestranddnabreakrepairgenespolymorphisminindigenousandmigrantpopulations
AT vgdruzhinin moleculargeneticanalysisofdoublestranddnabreakrepairgenespolymorphisminindigenousandmigrantpopulations
AT aatimofeeva moleculargeneticanalysisofdoublestranddnabreakrepairgenespolymorphisminindigenousandmigrantpopulations
AT avryzhkova moleculargeneticanalysisofdoublestranddnabreakrepairgenespolymorphisminindigenousandmigrantpopulations
AT avlarionov moleculargeneticanalysisofdoublestranddnabreakrepairgenespolymorphisminindigenousandmigrantpopulations