CDPK2A and CDPK1 form a signaling module upstream of Toxoplasma motility

ABSTRACT In apicomplexan parasites, the transition between replication and dissemination is regulated by fluctuations in cytosolic calcium concentrations, transduced in part by calcium-dependent protein kinases (CDPKs). We examined the role of CDPK2A in the lytic cycle of Toxoplasma, analyzing its r...

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Bibliographic Details
Main Authors: Emily Shortt, Caroline G. Hackett, Rachel V. Stadler, Robyn S. Kent, Alice L. Herneisen, Gary E. Ward, Sebastian Lourido
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01358-23