Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments
Objective:This study was conducted to investigate the effects of ionizing radiation (IR) and non-ionizing radiation (NIR) on oxidative stress and the total antioxidant status (TAS) in men working in radiation environments.Methods:The serum values of total oxidant status (TOS), malondialdehyde (MDA),...
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| Format: | Article |
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Galenos Publishing House
2016-12-01
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| Series: | Bezmiâlem Science |
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http://bezmialemscience.org/archives/archive-detail/article-preview/effects-of-onizing-and-non-onizing-radiation-on-ox/20323
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| _version_ | 1797912598815965184 |
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| author | Hakim ÇELİK İsmail KOYUNCU Ali Ziya KARAKILÇIK Ataman GÖNEL Davud MUSA |
| author_facet | Hakim ÇELİK İsmail KOYUNCU Ali Ziya KARAKILÇIK Ataman GÖNEL Davud MUSA |
| author_sort | Hakim ÇELİK |
| collection | DOAJ |
| description | Objective:This study was conducted to investigate the effects of ionizing radiation (IR) and non-ionizing radiation (NIR) on oxidative stress and the total antioxidant status (TAS) in men working in radiation environments.Methods:The serum values of total oxidant status (TOS), malondialdehyde (MDA), and protein carbonyl (PC) in men exposed to radiation and a control group were determined. In addition, the values of the total antioxidant status (TAS) were measured in serum, and the oxidative stress index (OSI) was calculated to determine the oxidative stress. Data were analyzed by SPSS 20.0 (Chicago, IL, USA).Results:While the serum values of PC, MDA, TOS, and OSI were significantly higher in the IR group than in the control group, those of TAS were significantly lower (p<0.001, p=0.003, p<0.001, p<0.001, and p= 0.002, respectively). The serum values of PC, TOS, and OSI were significantly higher in the NIR group than in the control group (p<0.001, p=0.021, and p=0.010, respectively). In contrast, there were no significant differences in the values of TAS and MDA (p>0.05 and p>0.05, respectively) in the same groups.Conclusion:Based on these results, we determined that it had been damaged the balance between oxidants and antioxidant status in the IR and NIR groups. This effect of oxidative stress may cause a lot of damage to cellular macromolecules including lipids, proteins, and DNA. |
| first_indexed | 2024-04-10T11:58:26Z |
| format | Article |
| id | doaj.art-a7af2677382d402db9021f32db68bacf |
| institution | Directory Open Access Journal |
| issn | 2148-2373 2148-2373 |
| language | English |
| last_indexed | 2024-04-10T11:58:26Z |
| publishDate | 2016-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Bezmiâlem Science |
| spelling | doaj.art-a7af2677382d402db9021f32db68bacf2023-02-15T16:16:43ZengGalenos Publishing HouseBezmiâlem Science2148-23732148-23732016-12-014310610910.14235/bs.2016.87213049054Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation EnvironmentsHakim ÇELİK0İsmail KOYUNCU1Ali Ziya KARAKILÇIK2Ataman GÖNEL3Davud MUSA4 Department of Physiology, Harran University School of Medicine, Şanlıurfa, Turkey Department of Medical Biochemistry, Harran University School of Medicine, Şanlıurfa, Turkey Department of Physiology, Harran University School of Medicine, Şanlıurfa, Turkey Clinic of Medical Biochemistry, Akçakale State Hospital, Şanlıurfa, Turkey Division of Biology, School of Social Sciences and Humanities, Şanlıurfa, Turkey Objective:This study was conducted to investigate the effects of ionizing radiation (IR) and non-ionizing radiation (NIR) on oxidative stress and the total antioxidant status (TAS) in men working in radiation environments.Methods:The serum values of total oxidant status (TOS), malondialdehyde (MDA), and protein carbonyl (PC) in men exposed to radiation and a control group were determined. In addition, the values of the total antioxidant status (TAS) were measured in serum, and the oxidative stress index (OSI) was calculated to determine the oxidative stress. Data were analyzed by SPSS 20.0 (Chicago, IL, USA).Results:While the serum values of PC, MDA, TOS, and OSI were significantly higher in the IR group than in the control group, those of TAS were significantly lower (p<0.001, p=0.003, p<0.001, p<0.001, and p= 0.002, respectively). The serum values of PC, TOS, and OSI were significantly higher in the NIR group than in the control group (p<0.001, p=0.021, and p=0.010, respectively). In contrast, there were no significant differences in the values of TAS and MDA (p>0.05 and p>0.05, respectively) in the same groups.Conclusion:Based on these results, we determined that it had been damaged the balance between oxidants and antioxidant status in the IR and NIR groups. This effect of oxidative stress may cause a lot of damage to cellular macromolecules including lipids, proteins, and DNA. http://bezmialemscience.org/archives/archive-detail/article-preview/effects-of-onizing-and-non-onizing-radiation-on-ox/20323 Ionizing radiationnon-ionizing radiationtotal oxidant statusmalondialdehydeprotein carbonyltotal antioxidant statusoxidative stress index |
| spellingShingle | Hakim ÇELİK İsmail KOYUNCU Ali Ziya KARAKILÇIK Ataman GÖNEL Davud MUSA Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments Bezmiâlem Science Ionizing radiation non-ionizing radiation total oxidant status malondialdehyde protein carbonyl total antioxidant status oxidative stress index |
| title | Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments |
| title_full | Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments |
| title_fullStr | Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments |
| title_full_unstemmed | Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments |
| title_short | Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments |
| title_sort | effects of ionizing and non ionizing radiation on oxidative stress and the total antioxidant status in humans working in radiation environments |
| topic | Ionizing radiation non-ionizing radiation total oxidant status malondialdehyde protein carbonyl total antioxidant status oxidative stress index |
| url |
http://bezmialemscience.org/archives/archive-detail/article-preview/effects-of-onizing-and-non-onizing-radiation-on-ox/20323
|
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