Coping with viral diversity in HIV vaccine design.

Coping with viral diversity in HIV vaccine design.

The ability of human immunodeficiency virus type 1 (HIV-1) to develop high levels of genetic diversity, and thereby acquire mutations to escape immune pressures, contributes to the difficulties in producing a vaccine. Possibly no single HIV-1 sequence can induce sufficiently broad immunity to protec...

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Bibliographic Details
Main Authors: David C Nickle, Morgane Rolland, Mark A Jensen, Sergei L Kosakovsky Pond, Wenjie Deng, Mark Seligman, David Heckerman, James I Mullins, Nebojsa Jojic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1857809?pdf=render

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http://europepmc.org/articles/PMC1857809?pdf=render

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