Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties
Synthetic apatites are widely used both in the dental and the orthopaedic fields due to their similarity in composition with the inorganic phase of hard tissues. Biologic apatites are not pure hydroxyapatite (HA), but are calcium-deficient apatites with magnesium and carbonate as minor but important...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)
2013-04-01
|
| Series: | Materials Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392013000400012&tlng=en |
| _version_ | 1818731437314015232 |
|---|---|
| author | Marcia S. Sader Kanthi Lewis Gloria A. Soares Racquel Z. LeGeros |
| author_facet | Marcia S. Sader Kanthi Lewis Gloria A. Soares Racquel Z. LeGeros |
| author_sort | Marcia S. Sader |
| collection | DOAJ |
| description | Synthetic apatites are widely used both in the dental and the orthopaedic fields due to their similarity in composition with the inorganic phase of hard tissues. Biologic apatites are not pure hydroxyapatite (HA), but are calcium-deficient apatites with magnesium and carbonate as minor but important substituents. The aim of the present study was to produce a more soluble biomaterial through the simultaneous substitution of magnesium and carbonate in the apatite structure to accelerate the degradation time in the body. The physico-chemical and dissolution properties of unsintered magnesium and carbonate-substituted apatite (MCAp) with similar Mg/Ca molar ratio (0.03) and varying C/P molar ratio were evaluated. The resultant powders were characterised using several techniques, such as FTIR, TGA, XRD, ICP and SEM, while the release of calcium ions in a pH 6 solution was monitored using a Ca-ion selective electrode. The results showed a decrease of crystallite size and an increase in the release of calcium to the medium as the carbonate content in the samples increased. |
| first_indexed | 2024-12-17T23:17:40Z |
| format | Article |
| id | doaj.art-a7b138c69af44366a678bf02ac742de3 |
| institution | Directory Open Access Journal |
| issn | 1516-1439 |
| language | English |
| last_indexed | 2024-12-17T23:17:40Z |
| publishDate | 2013-04-01 |
| publisher | Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol) |
| record_format | Article |
| series | Materials Research |
| spelling | doaj.art-a7b138c69af44366a678bf02ac742de32022-12-21T21:28:58ZengAssociação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)Materials Research1516-14392013-04-0116477978410.1590/S1516-14392013005000046Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical propertiesMarcia S. Sader0Kanthi Lewis1Gloria A. Soares2Racquel Z. LeGeros3Universidade Federal do Rio de JaneiroNew York UniversityUniversidade Federal do Rio de JaneiroNew York UniversitySynthetic apatites are widely used both in the dental and the orthopaedic fields due to their similarity in composition with the inorganic phase of hard tissues. Biologic apatites are not pure hydroxyapatite (HA), but are calcium-deficient apatites with magnesium and carbonate as minor but important substituents. The aim of the present study was to produce a more soluble biomaterial through the simultaneous substitution of magnesium and carbonate in the apatite structure to accelerate the degradation time in the body. The physico-chemical and dissolution properties of unsintered magnesium and carbonate-substituted apatite (MCAp) with similar Mg/Ca molar ratio (0.03) and varying C/P molar ratio were evaluated. The resultant powders were characterised using several techniques, such as FTIR, TGA, XRD, ICP and SEM, while the release of calcium ions in a pH 6 solution was monitored using a Ca-ion selective electrode. The results showed a decrease of crystallite size and an increase in the release of calcium to the medium as the carbonate content in the samples increased.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392013000400012&tlng=encalcium-deficient apatiteionic substitutionscrystallinitybone graft |
| spellingShingle | Marcia S. Sader Kanthi Lewis Gloria A. Soares Racquel Z. LeGeros Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties Materials Research calcium-deficient apatite ionic substitutions crystallinity bone graft |
| title | Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties |
| title_full | Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties |
| title_fullStr | Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties |
| title_full_unstemmed | Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties |
| title_short | Simultaneous incorporation of magnesium and carbonate in apatite: effect on physico-chemical properties |
| title_sort | simultaneous incorporation of magnesium and carbonate in apatite effect on physico chemical properties |
| topic | calcium-deficient apatite ionic substitutions crystallinity bone graft |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392013000400012&tlng=en |
| work_keys_str_mv | AT marciassader simultaneousincorporationofmagnesiumandcarbonateinapatiteeffectonphysicochemicalproperties AT kanthilewis simultaneousincorporationofmagnesiumandcarbonateinapatiteeffectonphysicochemicalproperties AT gloriaasoares simultaneousincorporationofmagnesiumandcarbonateinapatiteeffectonphysicochemicalproperties AT racquelzlegeros simultaneousincorporationofmagnesiumandcarbonateinapatiteeffectonphysicochemicalproperties |