Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery
Abstract Background Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a...
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-023-02016-4 |
| _version_ | 1797836633334087680 |
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| author | Marghich Omar Anis Tarek Bouassria Abdeslam Efoé-Ga Yawod Olivier Amouzou Ousadden Abdelmalek Ait Taleb Khalid El Bouhaddouti Hicham Mouaqit Ouadii Mazaz Khalid Rahili Mohamed Amine Benjelloun El Bachir Benizri Emmanuel |
| author_facet | Marghich Omar Anis Tarek Bouassria Abdeslam Efoé-Ga Yawod Olivier Amouzou Ousadden Abdelmalek Ait Taleb Khalid El Bouhaddouti Hicham Mouaqit Ouadii Mazaz Khalid Rahili Mohamed Amine Benjelloun El Bachir Benizri Emmanuel |
| author_sort | Marghich Omar |
| collection | DOAJ |
| description | Abstract Background Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a prevalence of acute renal failure (ARF) of 20%. The objective of this study was to establish the predictive factors of ARF in patients with protective ileostomy after surgery for rectal cancer from a bicentric study. Methods we conducted a bicentric retrospective cohort study to identify the risk factor of ARF. This study was carried out on 277 patients operated for rectal cancer with necessity of a protective ileostomy during the study period. ARF was measured at any endpoint between ileostomy creation and reversal. Multiple logistic regressions were performed to identify independent risk factors. Results A total of 277 patients were included, and 18% (n = 50) were readmitted for ARF. In multivariate logistic regression, increased age (OR 1.02, p = 0.01), Psychiatric diseases (OR 4.33, p = 0.014), Angiotensin II receptor blockers (OR 5.15, p < 0.001) and the ASA score ≥ 3 (OR 9.5, p < 0.001) were significantly associated with ARF. Conclusion Acute renal failure is a prevalent and significant event in the postoperative course of ileostomy patients. Patients at risk should be risk stratified before discharge and targeted for intensive preventive measures. |
| first_indexed | 2024-04-09T15:13:09Z |
| format | Article |
| id | doaj.art-a7b494a012ba4305b5a5206f60f793b1 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-04-09T15:13:09Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-a7b494a012ba4305b5a5206f60f793b12023-04-30T11:05:50ZengBMCBMC Surgery1471-24822023-04-012311510.1186/s12893-023-02016-4Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgeryMarghich Omar0Anis Tarek1Bouassria Abdeslam2Efoé-Ga Yawod Olivier Amouzou3Ousadden Abdelmalek4Ait Taleb Khalid5El Bouhaddouti Hicham6Mouaqit Ouadii7Mazaz Khalid8Rahili Mohamed Amine9Benjelloun El Bachir10Benizri Emmanuel11Department of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2General and Oncology Surgery Unit, Archet 2 Hospital, University Hospital of NiceDepartment of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2Department of Visceral Surgery, University Hospital Hassan 2General and Oncology Surgery Unit, Archet 2 Hospital, University Hospital of NiceFaculty of Medicine, Pharmacy and Dental Medicine, Sidi Mohamed Ben Abdellah UniversityGeneral and Oncology Surgery Unit, Archet 2 Hospital, University Hospital of NiceAbstract Background Despite the potential benefits of protective ileostomy in rectal surgery, diverting loop ileostomy construction is not free of specific medical consequences implying unplanned hospital readmissions. The most common reason for readmission in these patients is a dehydration with a prevalence of acute renal failure (ARF) of 20%. The objective of this study was to establish the predictive factors of ARF in patients with protective ileostomy after surgery for rectal cancer from a bicentric study. Methods we conducted a bicentric retrospective cohort study to identify the risk factor of ARF. This study was carried out on 277 patients operated for rectal cancer with necessity of a protective ileostomy during the study period. ARF was measured at any endpoint between ileostomy creation and reversal. Multiple logistic regressions were performed to identify independent risk factors. Results A total of 277 patients were included, and 18% (n = 50) were readmitted for ARF. In multivariate logistic regression, increased age (OR 1.02, p = 0.01), Psychiatric diseases (OR 4.33, p = 0.014), Angiotensin II receptor blockers (OR 5.15, p < 0.001) and the ASA score ≥ 3 (OR 9.5, p < 0.001) were significantly associated with ARF. Conclusion Acute renal failure is a prevalent and significant event in the postoperative course of ileostomy patients. Patients at risk should be risk stratified before discharge and targeted for intensive preventive measures.https://doi.org/10.1186/s12893-023-02016-4Rectal cancerProtective ileostomyRisk factorsAcute renal failure |
| spellingShingle | Marghich Omar Anis Tarek Bouassria Abdeslam Efoé-Ga Yawod Olivier Amouzou Ousadden Abdelmalek Ait Taleb Khalid El Bouhaddouti Hicham Mouaqit Ouadii Mazaz Khalid Rahili Mohamed Amine Benjelloun El Bachir Benizri Emmanuel Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery BMC Surgery Rectal cancer Protective ileostomy Risk factors Acute renal failure |
| title | Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| title_full | Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| title_fullStr | Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| title_full_unstemmed | Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| title_short | Risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| title_sort | risk factors of acute renal failure in patients with protective ileostomy after rectal cancer surgery |
| topic | Rectal cancer Protective ileostomy Risk factors Acute renal failure |
| url | https://doi.org/10.1186/s12893-023-02016-4 |
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