MRGBP, a member of the NuA4 complex, inhibits DNA double‐strand break repair

MRGBP, a member of the NuA4 complex, inhibits DNA double‐strand break repair

The repair of DNA breaks takes place in the context of chromatin and thus involves the activity of chromatin remodelers. The nucleosome acetyltransferase of H4 (NuA4) remodeler complex enables DNA break repair by relaxing flanking chromatin. Here, we show that MRG domain binding protein (MRGBP), a m...

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Bibliographic Details
Main Authors: Sabrina Rivero, Guillermo Rodríguez‐Real, Inés Marín, Pablo Huertas
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:FEBS Open Bio
Subjects:
DNA repair
DNA‐end resection
MRGBP
recombination
TIP60
Online Access:https://doi.org/10.1002/2211-5463.13071

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