Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma

Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma

Background: Mounting evidence underscores the importance of cell communication within the tumor microenvironment, which is pivotal in tumor proliferation, invasion, and metastasis. Exosomes play a crucial role in cell-to-cell communication. Although single-cell RNA sequencing (scRNA-seq) provides in...

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Bibliographic Details
Main Authors: Rong Tang, Zifeng Zhang, Jin Xu, Wei Wang, Qingcai Meng, Yuan Liu, Qiong Du, Chen Liang, Jie Hua, Bo Zhang, Xianjun Yu, Si Shi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Pancreatic cancer
MiRNA
Immune microenvironment
Exosome
Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024001077

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http://www.sciencedirect.com/science/article/pii/S2001037024001077

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