CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer

CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer

Abstract Background Bladder cancer (BCa) is the fourth most common malignant tumor with a poor prognosis worldwide. Further exploration and research are needed to unmask the underlying roles and molecular mechanisms of circular RNAs. In the current study, our findings showed that circXRN2 suppresses...

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Bibliographic Details
Main Authors: Bo Xie, Juntao Lin, Xianwu Chen, Xuejian Zhou, Yan Zhang, Mengjing Fan, Jiayong Xiang, Ning He, Zhenghui Hu, Feifan Wang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Molecular Cancer
Subjects:
Bladder cancer
circXRN2
Hippo pathway
Histone lactylation
Tumor progression
Online Access:https://doi.org/10.1186/s12943-023-01856-1

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