One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants
Marine bio-resources are being extensively researched as a priceless supply of substances with therapeutic potential. This work report the first time attempt made towards the green synthesis of gold nanoparticles (AuNPs) using the aqueous extract of marine soft coral (SCE), Sarcophyton crassocaule....
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023018753 |
| _version_ | 1827972487112032256 |
|---|---|
| author | Samson Rokkarukala Tijo Cherian Chinnasamy Ragavendran Raju Mohanraju Chinnaperumal Kamaraj Yosif Almoshari Ahmed Albariqi Muhammad H. Sultan Abdullah Alsalhi Syam Mohan |
| author_facet | Samson Rokkarukala Tijo Cherian Chinnasamy Ragavendran Raju Mohanraju Chinnaperumal Kamaraj Yosif Almoshari Ahmed Albariqi Muhammad H. Sultan Abdullah Alsalhi Syam Mohan |
| author_sort | Samson Rokkarukala |
| collection | DOAJ |
| description | Marine bio-resources are being extensively researched as a priceless supply of substances with therapeutic potential. This work report the first time attempt made towards the green synthesis of gold nanoparticles (AuNPs) using the aqueous extract of marine soft coral (SCE), Sarcophyton crassocaule. The synthesis was conducted under optimized conditions and the visual coloration of reaction mixture changed from yellowish to ruby red at 540 nm. The electron microscopic (TEM, SEM) studies exhibited spherical and oval shaped SCE-AuNPs in the size ranges of 5–50 nm. The organic compounds present in SCE were primarily responsible for the biological reduction of gold ions validated by FT-IR while the zeta potential confirmed the overall stability of SCE-AuNPs. The synthesized SCE-AuNPs exhibited variety of biological efficacies like antibacterial, antioxidant and anti-diabetic in nature. The biosynthesized SCE-AuNPs demonstrated remarkable bactericidal efficacy against clinically significant bacterial pathogens with inhibition zones of mm. Additionally, SCE-AuNPs exhibited greater antioxidant capacity in terms of DPPH: 85 ± 0.32% and RP: 82 ± 0.41%). The ability of enzyme inhibition assays to inhibit α-amylase (68 ± 0.21%) and α-glucosidase (79 ± 0.2%) was quite high. The study also highlighted the spectroscopic analysis of the biosynthesized SCE-AuNPs' catalytic effectiveness of 91% in the reduction processes of the perilous organic dyes, exhibiting pseudo-first order kinetics. |
| first_indexed | 2024-04-09T19:22:34Z |
| format | Article |
| id | doaj.art-a7c2d09354764fd989850c283aea47cd |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-09T19:22:34Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-a7c2d09354764fd989850c283aea47cd2023-04-05T08:27:55ZengElsevierHeliyon2405-84402023-03-0193e14668One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutantsSamson Rokkarukala0Tijo Cherian1Chinnasamy Ragavendran2Raju Mohanraju3Chinnaperumal Kamaraj4Yosif Almoshari5Ahmed Albariqi6Muhammad H. Sultan7Abdullah Alsalhi8Syam Mohan9Department of Ocean Studies and Marine Biology, Pondicherry University, Port Blair campus, Brookshabad, Port Blair, Andamans- 744112Department of Ocean Studies and Marine Biology, Pondicherry University, Port Blair campus, Brookshabad, Port Blair, Andamans- 744112; Corresponding author.Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IndiaDepartment of Ocean Studies and Marine Biology, Pondicherry University, Port Blair campus, Brookshabad, Port Blair, Andamans- 744112Interdisciplinary Institute of Indian System of Medicine (IIISM), Drug Testing Laboratory, Directorate of Research, SRM Institute Science and Technology, Kattankulathur - 603 203, Tamil Nadu, IndiaDepartment of pharmaceutics, College of pharmacy, Jazan University,P.O. Box 114, Jazan 45142, Saudi ArabiaDepartment of pharmaceutics, College of pharmacy, Jazan University,P.O. Box 114, Jazan 45142, Saudi ArabiaDepartment of pharmaceutics, College of pharmacy, Jazan University,P.O. Box 114, Jazan 45142, Saudi ArabiaDepartment of pharmaceutics, College of pharmacy, Jazan University,P.O. Box 114, Jazan 45142, Saudi ArabiaSubstance Abuse and Toxicology Research Centre, Jazan University, Jazan, Saudi Arabia; School of Health Sciences, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India; Center for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical science, Saveetha University, Chennai, India; Corresponding author. .Marine bio-resources are being extensively researched as a priceless supply of substances with therapeutic potential. This work report the first time attempt made towards the green synthesis of gold nanoparticles (AuNPs) using the aqueous extract of marine soft coral (SCE), Sarcophyton crassocaule. The synthesis was conducted under optimized conditions and the visual coloration of reaction mixture changed from yellowish to ruby red at 540 nm. The electron microscopic (TEM, SEM) studies exhibited spherical and oval shaped SCE-AuNPs in the size ranges of 5–50 nm. The organic compounds present in SCE were primarily responsible for the biological reduction of gold ions validated by FT-IR while the zeta potential confirmed the overall stability of SCE-AuNPs. The synthesized SCE-AuNPs exhibited variety of biological efficacies like antibacterial, antioxidant and anti-diabetic in nature. The biosynthesized SCE-AuNPs demonstrated remarkable bactericidal efficacy against clinically significant bacterial pathogens with inhibition zones of mm. Additionally, SCE-AuNPs exhibited greater antioxidant capacity in terms of DPPH: 85 ± 0.32% and RP: 82 ± 0.41%). The ability of enzyme inhibition assays to inhibit α-amylase (68 ± 0.21%) and α-glucosidase (79 ± 0.2%) was quite high. The study also highlighted the spectroscopic analysis of the biosynthesized SCE-AuNPs' catalytic effectiveness of 91% in the reduction processes of the perilous organic dyes, exhibiting pseudo-first order kinetics.http://www.sciencedirect.com/science/article/pii/S2405844023018753Sarcophyton crassocauleSoft coralGold nanoparticlesAntibacterialAntioxidantAntidiabetic |
| spellingShingle | Samson Rokkarukala Tijo Cherian Chinnasamy Ragavendran Raju Mohanraju Chinnaperumal Kamaraj Yosif Almoshari Ahmed Albariqi Muhammad H. Sultan Abdullah Alsalhi Syam Mohan One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants Heliyon Sarcophyton crassocaule Soft coral Gold nanoparticles Antibacterial Antioxidant Antidiabetic |
| title | One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants |
| title_full | One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants |
| title_fullStr | One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants |
| title_full_unstemmed | One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants |
| title_short | One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants |
| title_sort | one pot green synthesis of gold nanoparticles using sarcophyton crassocaule a marine soft coral assessing biological potentialities of antibacterial antioxidant anti diabetic and catalytic degradation of toxic organic pollutants |
| topic | Sarcophyton crassocaule Soft coral Gold nanoparticles Antibacterial Antioxidant Antidiabetic |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023018753 |
| work_keys_str_mv | AT samsonrokkarukala onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT tijocherian onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT chinnasamyragavendran onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT rajumohanraju onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT chinnaperumalkamaraj onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT yosifalmoshari onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT ahmedalbariqi onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT muhammadhsultan onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT abdullahalsalhi onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants AT syammohan onepotgreensynthesisofgoldnanoparticlesusingsarcophytoncrassocauleamarinesoftcoralassessingbiologicalpotentialitiesofantibacterialantioxidantantidiabeticandcatalyticdegradationoftoxicorganicpollutants |