Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors

Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors

Herein, we describe the global comparison of miRNAs in human pancreatic cancer tumors, adjacent normal tissue, and matched patient-derived xenograft models using microarray screening. RNA was extracted from seven tumor, five adjacent normal, and eight FI PDX tumor samples and analyzed by Affymetrix...

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Bibliographic Details
Main Authors: Fiona O’Neill, Taylor-Jade Allen-Coyle, Sandra Roche, Justine Meiller, Neil T. Conlon, Niall Swan, Robert M. Straubinger, Justin Geoghegan, Ninfa L. Straubinger, Kevin Conlon, Ray McDermott, Finbarr O’Sullivan, Michael Henry, Paula Meleady, Gerard McVey, Robert O’Connor, Michael Moriarty, Martin Clynes
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Life
Subjects:
pancreatic cancer
miRNA
PDX
tumour
Online Access:https://www.mdpi.com/2075-1729/13/3/608

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