Copper(I)-Catalyzed [ 3+ 2] Cycloaddition of 3-Azidoquinoline-2,4(1H,3H)-diones with Terminal Alkynes

Copper(I)-Catalyzed [ 3+ 2] Cycloaddition of 3-Azidoquinoline-2,4(1H,3H)-diones with Terminal Alkynes

3-Azidoquinoline-2,4(1H,3H)-diones 1, which are readily available from 4-hydroxyquinolin-2(1H)-ones 4 via 3-chloroquinoline-2,4(1H,3H)-diones 5, afford, in copper(I)-catalyzed [3 + 2] cycloaddition reaction with terminal acetylenes, 1,4-disubstituted 1,2,3-triazoles 3 in moderate to excellent yields...

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Bibliographic Details
Main Authors: Stanislav Kafka, Sylvia Hauke, Arjana Salcinovic, Otto Soidinsalo, Damijana Urankar, Janez Kosmrlj
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
cycloaddition
azides
quinoline-2,4(1H,3H)-diones
terminal alkynes
1,2,3-triazoles
Online Access:http://www.mdpi.com/1420-3049/16/5/4070/

Internet

http://www.mdpi.com/1420-3049/16/5/4070/

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