GADD45A does not promote DNA demethylation.
Although DNA methylation patterns in somatic cells are thought to be relatively stable, they undergo dramatic changes during embryonic development, gametogenesis, and during malignant transformation. The enzymology of DNA methyltransferases is well understood, but the mechanism that removes methylat...
| Main Authors: | , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Public Library of Science (PLoS)
2008-03-01
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| 叢編: | PLoS Genetics |
| 在線閱讀: | http://europepmc.org/articles/PMC2265528?pdf=render |