Suppression of IgE-Independent Degranulation of Murine Connective Tissue-Type Mast Cells by Dexamethasone

Suppression of IgE-Independent Degranulation of Murine Connective Tissue-Type Mast Cells by Dexamethasone

Steroidal anti-inflammatory drugs are widely used for the treatment of chronic cutaneous inflammation, such as atopic dermatitis, although it remains unknown how they modulate cutaneous mast cell functions. We investigated the effects of prolonged treatment with a synthetic glucocorticoid, dexametha...

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Bibliographic Details
Main Authors: Keiko Yamada, Hitomi Sato, Kazuma Sakamaki, Mayumi Kamada, Yasushi Okuno, Nobuyuki Fukuishi, Kazuyuki Furuta, Satoshi Tanaka
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
mast cell
dexamethasone
trimeric G protein
Mrgpr
skin
inflammation
Online Access:https://www.mdpi.com/2073-4409/8/2/112

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