Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats
Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and S...
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212&lng=en&tlng=en |
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| author | André Junior Santana Jean Carlos Debastiani Pâmela Buratti Ana Luiza Peretti Regina Inês Kunz Rose Meire Costa Brancalhão Lucinéia de Fátima Chasko Ribeiro Márcia Miranda Torrejais Gladson Ricardo Flor Bertolini |
| author_facet | André Junior Santana Jean Carlos Debastiani Pâmela Buratti Ana Luiza Peretti Regina Inês Kunz Rose Meire Costa Brancalhão Lucinéia de Fátima Chasko Ribeiro Márcia Miranda Torrejais Gladson Ricardo Flor Bertolini |
| author_sort | André Junior Santana |
| collection | DOAJ |
| description | Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury. |
| first_indexed | 2024-12-11T22:50:06Z |
| format | Article |
| id | doaj.art-a7c9be0e685c437d8db6355dbf68659f |
| institution | Directory Open Access Journal |
| issn | 2317-6385 |
| language | English |
| last_indexed | 2024-12-11T22:50:06Z |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-a7c9be0e685c437d8db6355dbf68659f2022-12-22T00:47:29ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-638516110.1590/s1679-45082018ao4137S1679-45082018000100212Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar ratsAndré Junior SantanaJean Carlos DebastianiPâmela BurattiAna Luiza PerettiRegina Inês KunzRose Meire Costa BrancalhãoLucinéia de Fátima Chasko RibeiroMárcia Miranda TorrejaisGladson Ricardo Flor BertoliniAbstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212&lng=en&tlng=enNervos periféricosFibras musculares esqueléticasExercícioNervo isquiático/lesõesProteínasRatos Wistar |
| spellingShingle | André Junior Santana Jean Carlos Debastiani Pâmela Buratti Ana Luiza Peretti Regina Inês Kunz Rose Meire Costa Brancalhão Lucinéia de Fátima Chasko Ribeiro Márcia Miranda Torrejais Gladson Ricardo Flor Bertolini Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats Einstein (São Paulo) Nervos periféricos Fibras musculares esqueléticas Exercício Nervo isquiático/lesões Proteínas Ratos Wistar |
| title | Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
| title_full | Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
| title_fullStr | Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
| title_full_unstemmed | Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
| title_short | Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
| title_sort | sericin and swimming on histomorphometric parameters of denervated plantar muscle in wistar rats |
| topic | Nervos periféricos Fibras musculares esqueléticas Exercício Nervo isquiático/lesões Proteínas Ratos Wistar |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212&lng=en&tlng=en |
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