Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur
<b>Background—</b>Though physiologic regurgitation of the right-sided cardiac valves is well recognized in dogs and other mammals, the prevalence of trace insufficiency of the mitral and aortic valves in clinically healthy, young adult dogs is unknown. <b>Methods—</b>In this...
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MDPI AG
2022-09-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/18/2442 |
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| author | Maxime V. de Jong Peter A. J. Leegwater Hille Fieten Viktor Szatmári |
| author_facet | Maxime V. de Jong Peter A. J. Leegwater Hille Fieten Viktor Szatmári |
| author_sort | Maxime V. de Jong |
| collection | DOAJ |
| description | <b>Background—</b>Though physiologic regurgitation of the right-sided cardiac valves is well recognized in dogs and other mammals, the prevalence of trace insufficiency of the mitral and aortic valves in clinically healthy, young adult dogs is unknown. <b>Methods—</b>In this observational cross-sectional study, 50 clinically healthy, young adult Labrador retrievers without an audible heart murmur were enrolled. All dogs were bred and owned by a single organization. Cardiac screening was requested for all dogs that were intended for breeding. These dogs underwent a cardiac auscultation and transthoracic echocardiography by a veterinary cardiology specialist. If mitral or aortic valve regurgitation was noticed, the jet size was subjectively assessed on color Doppler echocardiography. Pedigree analysis was performed to reveal a possible hereditary background of mitral valve regurgitation. <b>Results—</b>The prevalence of trivial mitral valve regurgitation was 52% with no significant predisposition to gender (<i>p</i> = 0.86) or haircoat color (<i>p</i> = 0.68). The prevalence of aortic valve regurgitation was 4%. Pedigree analysis for mitral valve regurgitation showed familial clustering, suggesting a hereditary background of the trait. <b>Conclusions—</b>The prevalence of silent trace mitral valve regurgitation in young adult Labrador retrievers was high. Because the regurgitant jet was trivial in all dogs, it is probably physiologic. |
| first_indexed | 2024-03-10T00:55:58Z |
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| id | doaj.art-a7ca73cc9abb48acb6e64cb0db4c1444 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T00:55:58Z |
| publishDate | 2022-09-01 |
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| series | Animals |
| spelling | doaj.art-a7ca73cc9abb48acb6e64cb0db4c14442023-11-23T14:42:58ZengMDPI AGAnimals2076-26152022-09-011218244210.3390/ani12182442Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart MurmurMaxime V. de Jong0Peter A. J. Leegwater1Hille Fieten2Viktor Szatmári3Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The NetherlandsClinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The NetherlandsClinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The NetherlandsClinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands<b>Background—</b>Though physiologic regurgitation of the right-sided cardiac valves is well recognized in dogs and other mammals, the prevalence of trace insufficiency of the mitral and aortic valves in clinically healthy, young adult dogs is unknown. <b>Methods—</b>In this observational cross-sectional study, 50 clinically healthy, young adult Labrador retrievers without an audible heart murmur were enrolled. All dogs were bred and owned by a single organization. Cardiac screening was requested for all dogs that were intended for breeding. These dogs underwent a cardiac auscultation and transthoracic echocardiography by a veterinary cardiology specialist. If mitral or aortic valve regurgitation was noticed, the jet size was subjectively assessed on color Doppler echocardiography. Pedigree analysis was performed to reveal a possible hereditary background of mitral valve regurgitation. <b>Results—</b>The prevalence of trivial mitral valve regurgitation was 52% with no significant predisposition to gender (<i>p</i> = 0.86) or haircoat color (<i>p</i> = 0.68). The prevalence of aortic valve regurgitation was 4%. Pedigree analysis for mitral valve regurgitation showed familial clustering, suggesting a hereditary background of the trait. <b>Conclusions—</b>The prevalence of silent trace mitral valve regurgitation in young adult Labrador retrievers was high. Because the regurgitant jet was trivial in all dogs, it is probably physiologic.https://www.mdpi.com/2076-2615/12/18/2442auscultationcongenitalhereditaryphysiologic regurgitationvalve dysplasia |
| spellingShingle | Maxime V. de Jong Peter A. J. Leegwater Hille Fieten Viktor Szatmári Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur Animals auscultation congenital hereditary physiologic regurgitation valve dysplasia |
| title | Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur |
| title_full | Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur |
| title_fullStr | Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur |
| title_full_unstemmed | Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur |
| title_short | Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur |
| title_sort | prevalence of echocardiographic evidence of trace mitral and aortic valve regurgitation in 50 clinically healthy young adult labrador retrievers without heart murmur |
| topic | auscultation congenital hereditary physiologic regurgitation valve dysplasia |
| url | https://www.mdpi.com/2076-2615/12/18/2442 |
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