Genetic variation in human drug-related genes
Abstract Background Variability in drug efficacy and adverse effects are observed in clinical practice. While the extent of genetic variability in classic pharmacokinetic genes is rather well understood, the role of genetic variation in drug targets is typically less studied. Methods Based on 60,706...
Hlavní autoři: | Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks |
---|---|
Médium: | Článek |
Jazyk: | English |
Vydáno: |
BMC
2017-12-01
|
Edice: | Genome Medicine |
Témata: | |
On-line přístup: | http://link.springer.com/article/10.1186/s13073-017-0502-5 |
Podobné jednotky
-
A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort
Autor: Kathrin Klein, a další
Vydáno: (2019-01-01) -
Pharmacogenomics-Based Detection of Variants Involved in Pain, Anti-inflammatory and Immunomodulating Agents Pathways by Whole Exome Sequencing and Deep in Silico Investigations Revealed Novel Chemical Carcinogenesis and Cancer Risks
Autor: Alireza Sharafshah, a další
Vydáno: (2025-02-01) -
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing
Autor: Daniel Felipe Silgado-Guzmán, a další
Vydáno: (2022-06-01) -
PHARMACOGENETIC TESTING OPPORTUNITIES IN CARDIOLOGY BASED ON EXOME SEQUENCING
Autor: N. V. Shcherbakova, a další
Vydáno: (2015-09-01) -
Editorial: How pharmacogenomics, epigenetics, and data analysis could improve anticancer treatment?
Autor: Abdeslam Jaafari, a další
Vydáno: (2022-11-01)