RNA-Targeting Splicing Modifiers: Drug Development and Screening Assays

RNA-Targeting Splicing Modifiers: Drug Development and Screening Assays

RNA splicing is an essential step in producing mature messenger RNA (mRNA) and other RNA species. Harnessing RNA splicing modifiers as a new pharmacological modality is promising for the treatment of diseases caused by aberrant splicing. This drug modality can be used for infectious diseases by disr...

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Bibliographic Details
Main Authors: Zhichao Tang, Junxing Zhao, Zach J. Pearson, Zarko V. Boskovic, Jingxin Wang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
alternative splicing
high-throughput screening
antisense oligonucleotide
small molecule
splicing modifier
RNA-targeting
Online Access:https://www.mdpi.com/1420-3049/26/8/2263

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