LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway

LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway

Radiation resistance poses a major clinical challenge in breast cancer (BC) treatment, but little is known about how long noncoding RNA (lncRNA) may regulate this phenomenon. Here, we reported that DUXAP8 was highly expressed in radioresistant BC tissues, and high expression of DUXAP8 was associated...

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Bibliographic Details
Main Authors: Changjiang Lei, Shaoting Li, Ying Fan, Li Hua, Qingyun Pan, Yuan Li, Zhixiong Long, Rui Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Cancer Biology & Therapy
Subjects:
lncrna duxap8
akt
ezh2
breast cancer
radioresistance
Online Access:http://dx.doi.org/10.1080/15384047.2022.2132008

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