Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality
Summary: Clustered protocadherin is a family of cell-surface recognition molecules implicated in neuronal connectivity that has a diverse isoform repertoire and homophilic binding specificity. Mice have 58 isoforms, encoded by Pcdhα, β, and γ gene clusters, and mutant mice lacking all isoforms died...
Main Authors: | Hiroaki Kobayashi, Kenji Takemoto, Makoto Sanbo, Masumi Hirabayashi, Takahiro Hirabayashi, Teruyoshi Hirayama, Hiroshi Kiyonari, Takaya Abe, Takeshi Yagi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222020399 |
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