In Situ “Humanization” of Porcine Bioprostheses: Demonstration of Tendon Bioprostheses Conversion into Human ACL and Possible Implications for Heart Valve Bioprostheses

In Situ “Humanization” of Porcine Bioprostheses: Demonstration of Tendon Bioprostheses Conversion into Human ACL and Possible Implications for Heart Valve Bioprostheses

This review describes the first studies on successful conversion of porcine soft-tissue bioprostheses into viable permanently functional tissue in humans. This process includes gradual degradation of the porcine tissue, with concomitant neo-vascularization and reconstruction of the implanted biopros...

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Bibliographic Details
Main Authors:	Uri Galili, Kevin R. Stone
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Bioengineering
Subjects:	heart valve bioprosthesis anterior cruciate ligament reconstruction porcine tendon bioprosthesis anti-Gal antibody anti-non gal antibody α-gal epitope
Online Access:	https://www.mdpi.com/2306-5354/8/1/10

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