Umbilical Cord Blood Research: Current and Future Perspectives
Umbilical cord blood (UCB) banking has become a new obstetrical trend. It offers expectant parents a biological insurance policy that can be used in the event of a child or family member's life-threatening illness and puts patients in a position of control over their own treatment options. Howe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2007-02-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/000000007783464623 |
| _version_ | 1818409124303470592 |
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| author | Jennifer D. Newcomb Paul R. Sanberg Stephen K. Klasko Alison E. Willing |
| author_facet | Jennifer D. Newcomb Paul R. Sanberg Stephen K. Klasko Alison E. Willing |
| author_sort | Jennifer D. Newcomb |
| collection | DOAJ |
| description | Umbilical cord blood (UCB) banking has become a new obstetrical trend. It offers expectant parents a biological insurance policy that can be used in the event of a child or family member's life-threatening illness and puts patients in a position of control over their own treatment options. However, its graduation to conventional therapy in the clinical realm relies on breakthrough research that will prove its efficacy for a range of ailments. Expanding the multipotent cells found within the mononuclear fraction of UCB so that adequate dosing can be achieved, effectively expanding desired cells ex vivo, establishing its safety and limitations in HLA-mismatched recipients, defining its mechanisms of action, and proving its utility in a wide variety of both rare and common illnesses and diseases are a few of the challenges left to tackle. Nevertheless, the field is moving fast and new UCB-based therapies are on the horizon. |
| first_indexed | 2024-12-14T09:54:38Z |
| format | Article |
| id | doaj.art-a7d8f3712b1f49268efede64035f2775 |
| institution | Directory Open Access Journal |
| issn | 0963-6897 1555-3892 |
| language | English |
| last_indexed | 2024-12-14T09:54:38Z |
| publishDate | 2007-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cell Transplantation |
| spelling | doaj.art-a7d8f3712b1f49268efede64035f27752022-12-21T23:07:26ZengSAGE PublishingCell Transplantation0963-68971555-38922007-02-011610.3727/000000007783464623Umbilical Cord Blood Research: Current and Future PerspectivesJennifer D. Newcomb0Paul R. Sanberg1Stephen K. Klasko2Alison E. Willing3Center of Excellence for Aging and Brain Repair, Department of Neurosurgery, University of South Florida, College of Medicine, Tampa, FL 33612, USACenter of Excellence for Aging and Brain Repair, Department of Neurosurgery, University of South Florida, College of Medicine, Tampa, FL 33612, USADepartment of Obstetrics and Gynecology, University of South Florida, College of Medicine, Tampa, FL 33612, USACenter of Excellence for Aging and Brain Repair, Department of Neurosurgery, University of South Florida, College of Medicine, Tampa, FL 33612, USAUmbilical cord blood (UCB) banking has become a new obstetrical trend. It offers expectant parents a biological insurance policy that can be used in the event of a child or family member's life-threatening illness and puts patients in a position of control over their own treatment options. However, its graduation to conventional therapy in the clinical realm relies on breakthrough research that will prove its efficacy for a range of ailments. Expanding the multipotent cells found within the mononuclear fraction of UCB so that adequate dosing can be achieved, effectively expanding desired cells ex vivo, establishing its safety and limitations in HLA-mismatched recipients, defining its mechanisms of action, and proving its utility in a wide variety of both rare and common illnesses and diseases are a few of the challenges left to tackle. Nevertheless, the field is moving fast and new UCB-based therapies are on the horizon.https://doi.org/10.3727/000000007783464623 |
| spellingShingle | Jennifer D. Newcomb Paul R. Sanberg Stephen K. Klasko Alison E. Willing Umbilical Cord Blood Research: Current and Future Perspectives Cell Transplantation |
| title | Umbilical Cord Blood Research: Current and Future Perspectives |
| title_full | Umbilical Cord Blood Research: Current and Future Perspectives |
| title_fullStr | Umbilical Cord Blood Research: Current and Future Perspectives |
| title_full_unstemmed | Umbilical Cord Blood Research: Current and Future Perspectives |
| title_short | Umbilical Cord Blood Research: Current and Future Perspectives |
| title_sort | umbilical cord blood research current and future perspectives |
| url | https://doi.org/10.3727/000000007783464623 |
| work_keys_str_mv | AT jenniferdnewcomb umbilicalcordbloodresearchcurrentandfutureperspectives AT paulrsanberg umbilicalcordbloodresearchcurrentandfutureperspectives AT stephenkklasko umbilicalcordbloodresearchcurrentandfutureperspectives AT alisonewilling umbilicalcordbloodresearchcurrentandfutureperspectives |