A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development

<p>Abstract</p> <p>Background</p> <p>Epidemiological studies have suggested that the encounter with commensal microorganisms during the neonatal period is essential for normal development of the host immune system. Basic research involving gnotobiotic mice has demonstra...

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Bibliographic Details
Main Authors: Yamamoto Masahiro, Yamaguchi Rui, Munakata Kaori, Takashima Kiyoe, Nishiyama Mitsue, Hioki Kyoji, Ohnishi Yasuyuki, Nagasaki Masao, Imoto Seiya, Miyano Satoru, Ishige Atsushi, Watanabe Kenji
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Genomics
Subjects:
Hygiene hypothesis
Germ-free
Toll-like receptor
Type 1 interferon
MetaGene Profiler
Online Access:http://www.biomedcentral.com/1471-2164/13/335

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