Relapsing Guillain-Barre syndrome in pregnancy and postpartum
Guillain-Barre syndrome (GBS) rarely complicates pregnancy, but can be associated with high maternal and perinatal morbidity if not properly identified and treated. A high index of suspicion, supportive measures, access to intensive care unit and intravenous immunoglobulin (IVIG) therapy are corners...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=3;spage=352;epage=354;aulast=Meenakshi-Sundaram |
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| author | S Meenakshi-Sundaram K Swaminathan S N Karthik S Bharathi |
| author_facet | S Meenakshi-Sundaram K Swaminathan S N Karthik S Bharathi |
| author_sort | S Meenakshi-Sundaram |
| collection | DOAJ |
| description | Guillain-Barre syndrome (GBS) rarely complicates pregnancy, but can be associated with high maternal and perinatal morbidity if not properly identified and treated. A high index of suspicion, supportive measures, access to intensive care unit and intravenous immunoglobulin (IVIG) therapy are cornerstones of management in GBS complicating pregnancy. Neurologists and Obstetricians should be aware of the risks of relapsing GBS in the immediate postpartum period. Surgery and anesthesia may be triggers for relapse in association with an overall increase in pro-inflammatory cytokines in the postpartum period. We report a unique case of GBS complicating pregnancy in the third trimester followed by a relapse in the postpartum period. She made a good recovery with supportive measures and a repeat course of IVIG during the relapse. |
| first_indexed | 2024-12-22T08:39:02Z |
| format | Article |
| id | doaj.art-a7db328d0e0d4211a970e74fe98a1948 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-22T08:39:02Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-a7db328d0e0d4211a970e74fe98a19482022-12-21T18:32:17ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492014-01-0117335235410.4103/0972-2327.138527Relapsing Guillain-Barre syndrome in pregnancy and postpartumS Meenakshi-SundaramK SwaminathanS N KarthikS BharathiGuillain-Barre syndrome (GBS) rarely complicates pregnancy, but can be associated with high maternal and perinatal morbidity if not properly identified and treated. A high index of suspicion, supportive measures, access to intensive care unit and intravenous immunoglobulin (IVIG) therapy are cornerstones of management in GBS complicating pregnancy. Neurologists and Obstetricians should be aware of the risks of relapsing GBS in the immediate postpartum period. Surgery and anesthesia may be triggers for relapse in association with an overall increase in pro-inflammatory cytokines in the postpartum period. We report a unique case of GBS complicating pregnancy in the third trimester followed by a relapse in the postpartum period. She made a good recovery with supportive measures and a repeat course of IVIG during the relapse.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=3;spage=352;epage=354;aulast=Meenakshi-SundaramGuillain-Barre syndromepregnancyrelapse |
| spellingShingle | S Meenakshi-Sundaram K Swaminathan S N Karthik S Bharathi Relapsing Guillain-Barre syndrome in pregnancy and postpartum Annals of Indian Academy of Neurology Guillain-Barre syndrome pregnancy relapse |
| title | Relapsing Guillain-Barre syndrome in pregnancy and postpartum |
| title_full | Relapsing Guillain-Barre syndrome in pregnancy and postpartum |
| title_fullStr | Relapsing Guillain-Barre syndrome in pregnancy and postpartum |
| title_full_unstemmed | Relapsing Guillain-Barre syndrome in pregnancy and postpartum |
| title_short | Relapsing Guillain-Barre syndrome in pregnancy and postpartum |
| title_sort | relapsing guillain barre syndrome in pregnancy and postpartum |
| topic | Guillain-Barre syndrome pregnancy relapse |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=3;spage=352;epage=354;aulast=Meenakshi-Sundaram |
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