IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION
Modeling of immune tolerance will eliminate the need for taking medications to prevent rejection. This review of available literature covers the immune mechanisms of allograft rejection and the ways of tolerance induction. The role of mesenchymal stem cells and using them for tolerance develo...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2017-09-01
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| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/179 |
| _version_ | 1826564624328163328 |
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| author | M. Sh. Khubutiya V. A. Gulyaev V. B. Khvatov V. L. Lemenev S. A. Kabanova M. S. Novruzbekov K. N. Lutsyk O. D. Olisov S. V. Zhuravel' G. V. Bulava D. Kh. Tsurova N. V. Borovkova А. S. Mironov L. N. Zimina |
| author_facet | M. Sh. Khubutiya V. A. Gulyaev V. B. Khvatov V. L. Lemenev S. A. Kabanova M. S. Novruzbekov K. N. Lutsyk O. D. Olisov S. V. Zhuravel' G. V. Bulava D. Kh. Tsurova N. V. Borovkova А. S. Mironov L. N. Zimina |
| author_sort | M. Sh. Khubutiya |
| collection | DOAJ |
| description | Modeling of immune tolerance will eliminate the need for taking medications to prevent rejection. This review of available literature covers the immune mechanisms of allograft rejection and the ways of tolerance induction. The role of mesenchymal stem cells and using them for tolerance development have been discussed. The authors also draw attention to the fact that blood transfusion from an organ donor leads to a decreased intensity of the immune response to donor cells in transplantation. |
| first_indexed | 2024-03-12T03:32:59Z |
| format | Article |
| id | doaj.art-a7e0ba8550524acdac91470f26c75467 |
| institution | Directory Open Access Journal |
| issn | 2074-0506 2542-0909 |
| language | English |
| last_indexed | 2025-03-14T10:22:49Z |
| publishDate | 2017-09-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj.art-a7e0ba8550524acdac91470f26c754672025-03-02T11:07:31ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092017-09-019321122510.23873/2074-0506-2017-9-3-211-225173IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATIONM. Sh. Khubutiya0V. A. Gulyaev1V. B. Khvatov2V. L. Lemenev3S. A. Kabanova4M. S. Novruzbekov5K. N. Lutsyk6O. D. Olisov7S. V. Zhuravel'8G. V. Bulava9D. Kh. Tsurova10N. V. Borovkova11А. S. Mironov12L. N. Zimina13N.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineModeling of immune tolerance will eliminate the need for taking medications to prevent rejection. This review of available literature covers the immune mechanisms of allograft rejection and the ways of tolerance induction. The role of mesenchymal stem cells and using them for tolerance development have been discussed. The authors also draw attention to the fact that blood transfusion from an organ donor leads to a decreased intensity of the immune response to donor cells in transplantation.https://www.jtransplantologiya.ru/jour/article/view/179organ transplantacute rejectionimmunological tolerance |
| spellingShingle | M. Sh. Khubutiya V. A. Gulyaev V. B. Khvatov V. L. Lemenev S. A. Kabanova M. S. Novruzbekov K. N. Lutsyk O. D. Olisov S. V. Zhuravel' G. V. Bulava D. Kh. Tsurova N. V. Borovkova А. S. Mironov L. N. Zimina IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION Трансплантология (Москва) organ transplant acute rejection immunological tolerance |
| title | IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION |
| title_full | IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION |
| title_fullStr | IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION |
| title_full_unstemmed | IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION |
| title_short | IMMUNOLOGICAL TOLERANCE IN ORGAN TRANSPLANTATION |
| title_sort | immunological tolerance in organ transplantation |
| topic | organ transplant acute rejection immunological tolerance |
| url | https://www.jtransplantologiya.ru/jour/article/view/179 |
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