Capturing heterogeneity in gene expression studies by surrogate variable analysis.
It has unambiguously been shown that genetic, environmental, demographic, and technical factors may have substantial effects on gene expression levels. In addition to the measured variable(s) of interest, there will tend to be sources of signal due to factors that are unknown, unmeasured, or too com...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1994707?pdf=render |