Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method

Background and Aims: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon′s up-an...

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Main Authors: Aparna Ashay Nerurkar, Wasim Shaikh, Bharati Anil Tendolkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=3;spage=324;epage=328;aulast=Nerurkar
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author Aparna Ashay Nerurkar
Wasim Shaikh
Bharati Anil Tendolkar
author_facet Aparna Ashay Nerurkar
Wasim Shaikh
Bharati Anil Tendolkar
author_sort Aparna Ashay Nerurkar
collection DOAJ
description Background and Aims: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon′s up-and-down method. Material and Methods: Prospective randomized controlled trial (n-60) was planned. I-gel or cLMA was inserted 60 s after propofol injection whose dose was calculated based on previous patients response as per Dixon′s up-and-down method. Propofol requirements for successful placement of devices was noted and compared. Difference between the groups was measured by ANOVA. A P < 0.05 was considered as statistically significant. Results: Significantly lower (P < 0.001) propofol dose was required for I-gel (2.02 ± 0.26 mg/kg) insertion than cLMA (2.70 ± 0.28 mg/kg). Conclusions: I-gel requires significantly lower dose of propofol for insertion when compared to cLMA.
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spelling doaj.art-a7e2f2b4495f4c468788108a7e3f35472022-12-21T23:02:10ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852015-01-0131332432810.4103/0970-9185.161666Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down methodAparna Ashay NerurkarWasim ShaikhBharati Anil TendolkarBackground and Aims: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon′s up-and-down method. Material and Methods: Prospective randomized controlled trial (n-60) was planned. I-gel or cLMA was inserted 60 s after propofol injection whose dose was calculated based on previous patients response as per Dixon′s up-and-down method. Propofol requirements for successful placement of devices was noted and compared. Difference between the groups was measured by ANOVA. A P < 0.05 was considered as statistically significant. Results: Significantly lower (P < 0.001) propofol dose was required for I-gel (2.02 ± 0.26 mg/kg) insertion than cLMA (2.70 ± 0.28 mg/kg). Conclusions: I-gel requires significantly lower dose of propofol for insertion when compared to cLMA.http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=3;spage=324;epage=328;aulast=NerurkarClassic laryngeal mask airwayDixon′s up-and-down methodI-gelpropofol
spellingShingle Aparna Ashay Nerurkar
Wasim Shaikh
Bharati Anil Tendolkar
Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
Journal of Anaesthesiology Clinical Pharmacology
Classic laryngeal mask airway
Dixon′s up-and-down method
I-gel
propofol
title Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
title_full Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
title_fullStr Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
title_full_unstemmed Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
title_short Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon′s up-and-down method
title_sort propofol requirement for insertion of i gel versus laryngeal mask airway a comparative dose finding study using dixon s up and down method
topic Classic laryngeal mask airway
Dixon′s up-and-down method
I-gel
propofol
url http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=3;spage=324;epage=328;aulast=Nerurkar
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