Loss of SMAD4 Is Sufficient to Promote Tumorigenesis in a Model of Dysplastic Barrett’s EsophagusSummary
Background & Aims: Esophageal adenocarcinoma (EAC) develops from its precursor Barrett’s esophagus through intermediate stages of low- and high-grade dysplasia. However, knowledge of genetic drivers and molecular mechanisms implicated in disease progression is limited. Herein, we investigate...
Main Authors: | Jovana R. Gotovac, Tanjina Kader, Julia V. Milne, Kenji M. Fujihara, Luis E. Lara-Gonzalez, Kylie L. Gorringe, Sangeetha N. Kalimuthu, Madawa W. Jayawardana, Cuong P. Duong, Wayne A. Phillips, Nicholas J. Clemons |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X21000606 |
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