Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies
This paper aims to review the evidence of the cellular activity on titanium samples exposed to Plasma of Argon (PoA) treatment. A systematic review was carried out based on the PRISMA statement by searching the Cochrane Library, PubMed, Web of Science, EMBASE and Scopus, up to October 2020. Papers w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/12/9/1219 |
| _version_ | 1827663062798172160 |
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| author | Massimo Carossa Davide Cavagnetto Francesca Mancini Alessandro Mosca Balma Federico Mussano |
| author_facet | Massimo Carossa Davide Cavagnetto Francesca Mancini Alessandro Mosca Balma Federico Mussano |
| author_sort | Massimo Carossa |
| collection | DOAJ |
| description | This paper aims to review the evidence of the cellular activity on titanium samples exposed to Plasma of Argon (PoA) treatment. A systematic review was carried out based on the PRISMA statement by searching the Cochrane Library, PubMed, Web of Science, EMBASE and Scopus, up to October 2020. Papers were selected according to PICOS format that is: Population (P): osteoblasts, fibroblasts, gingival cells; Intervention (I): PoA disinfection treatment; Comparison (C): untreated controls; Outcome (O): cell culture; Setting (S): in vitro assays. The quality assessment was performed according to the CRIS Guidelines (Checklist for Reporting In vitro Studies). A total of 661 articles were found, of which 16 were included. The quality assessment revealed an overall poor quality of the studies analyzed. In vitro studies on the potential of PoA showed a potential effect in promoting higher cell adhesion and protein adsorption in the earliest times (hours). This outcome was not so evident when later stages of cell growth on the surfaces were tested and compared to the control groups. Only one study was conducted in vivo on a human sample regarding abutment cleaning. No meta-analysis was conducted because of the variety of experimental settings, mixed methods and different cell lines studied. PoA seems to be effective in promoting cell adhesion and protein adsorption. The duration of this effect remains unclear. Further evidence is required to demonstrate the long-term efficacy of the treatment and to support the use of PoA treatment in clinical practice. |
| first_indexed | 2024-03-10T00:37:30Z |
| format | Article |
| id | doaj.art-a7e68fa883ed483e8cfcd75d66f8637d |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T00:37:30Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-a7e68fa883ed483e8cfcd75d66f8637d2023-11-23T15:14:54ZengMDPI AGBiomolecules2218-273X2022-09-01129121910.3390/biom12091219Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro StudiesMassimo Carossa0Davide Cavagnetto1Francesca Mancini2Alessandro Mosca Balma3Federico Mussano4Bone and Dental Bioengineering Lab, Department of Surgical Sciences, CIR Dental School, University of Torino, Via Nizza 230, 10126 Torino, ItalyBone and Dental Bioengineering Lab, Department of Surgical Sciences, CIR Dental School, University of Torino, Via Nizza 230, 10126 Torino, ItalyPrivate Practice, Via Venezia 7, Pieve Emanuele, 20090 Milan, ItalyBone and Dental Bioengineering Lab, Department of Surgical Sciences, CIR Dental School, University of Torino, Via Nizza 230, 10126 Torino, ItalyBone and Dental Bioengineering Lab, Department of Surgical Sciences, CIR Dental School, University of Torino, Via Nizza 230, 10126 Torino, ItalyThis paper aims to review the evidence of the cellular activity on titanium samples exposed to Plasma of Argon (PoA) treatment. A systematic review was carried out based on the PRISMA statement by searching the Cochrane Library, PubMed, Web of Science, EMBASE and Scopus, up to October 2020. Papers were selected according to PICOS format that is: Population (P): osteoblasts, fibroblasts, gingival cells; Intervention (I): PoA disinfection treatment; Comparison (C): untreated controls; Outcome (O): cell culture; Setting (S): in vitro assays. The quality assessment was performed according to the CRIS Guidelines (Checklist for Reporting In vitro Studies). A total of 661 articles were found, of which 16 were included. The quality assessment revealed an overall poor quality of the studies analyzed. In vitro studies on the potential of PoA showed a potential effect in promoting higher cell adhesion and protein adsorption in the earliest times (hours). This outcome was not so evident when later stages of cell growth on the surfaces were tested and compared to the control groups. Only one study was conducted in vivo on a human sample regarding abutment cleaning. No meta-analysis was conducted because of the variety of experimental settings, mixed methods and different cell lines studied. PoA seems to be effective in promoting cell adhesion and protein adsorption. The duration of this effect remains unclear. Further evidence is required to demonstrate the long-term efficacy of the treatment and to support the use of PoA treatment in clinical practice.https://www.mdpi.com/2218-273X/12/9/1219argonadsorptionbiocompatible materialstitaniumosteoblastfibroblast |
| spellingShingle | Massimo Carossa Davide Cavagnetto Francesca Mancini Alessandro Mosca Balma Federico Mussano Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies Biomolecules argon adsorption biocompatible materials titanium osteoblast fibroblast |
| title | Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies |
| title_full | Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies |
| title_fullStr | Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies |
| title_full_unstemmed | Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies |
| title_short | Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies |
| title_sort | plasma of argon treatment of the implant surface systematic review of in vitro studies |
| topic | argon adsorption biocompatible materials titanium osteoblast fibroblast |
| url | https://www.mdpi.com/2218-273X/12/9/1219 |
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