Monkeypox Virus Evolution before 2022 Outbreak
Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2023-02-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/29/2/22-0962_article |
| _version_ | 1828056119224827904 |
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| author | Eric Dumonteil Claudia Herrera Gilberto Sabino-Santos |
| author_facet | Eric Dumonteil Claudia Herrera Gilberto Sabino-Santos |
| author_sort | Eric Dumonteil |
| collection | DOAJ |
| description |
Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans.
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| first_indexed | 2024-04-10T20:49:22Z |
| format | Article |
| id | doaj.art-a7ec86e189f245168be7bf9da8efe4dc |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-10T20:49:22Z |
| publishDate | 2023-02-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-a7ec86e189f245168be7bf9da8efe4dc2023-01-23T18:22:16ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592023-02-0129245145310.3201/eid2902.220962Monkeypox Virus Evolution before 2022 OutbreakEric DumonteilClaudia HerreraGilberto Sabino-Santos Phylogenetic analysis of monkeypox virus genomes showed statistically significant divergence and nascent subclades during the 2022 mpox outbreak. Frequency of G>A/C>T transitions has increased in recent years, probably resulting from apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G (APOBEC3) deaminase editing. This microevolutionary pattern most likely reflects community spread of the virus and adaptation to humans. https://wwwnc.cdc.gov/eid/article/29/2/22-0962_articleMonkeypox virusMPXVmpoxtransmissionevolutionadaptation |
| spellingShingle | Eric Dumonteil Claudia Herrera Gilberto Sabino-Santos Monkeypox Virus Evolution before 2022 Outbreak Emerging Infectious Diseases Monkeypox virus MPXV mpox transmission evolution adaptation |
| title | Monkeypox Virus Evolution before 2022 Outbreak |
| title_full | Monkeypox Virus Evolution before 2022 Outbreak |
| title_fullStr | Monkeypox Virus Evolution before 2022 Outbreak |
| title_full_unstemmed | Monkeypox Virus Evolution before 2022 Outbreak |
| title_short | Monkeypox Virus Evolution before 2022 Outbreak |
| title_sort | monkeypox virus evolution before 2022 outbreak |
| topic | Monkeypox virus MPXV mpox transmission evolution adaptation |
| url | https://wwwnc.cdc.gov/eid/article/29/2/22-0962_article |
| work_keys_str_mv | AT ericdumonteil monkeypoxvirusevolutionbefore2022outbreak AT claudiaherrera monkeypoxvirusevolutionbefore2022outbreak AT gilbertosabinosantos monkeypoxvirusevolutionbefore2022outbreak |