Enhancement of the 7 alpha-dehydroxylase activity of a gram-positive intestinal anaerobe by Bacteroides and its significance in the 7-dehydroxylation of ursodeoxycholic acid

Enhancement of the 7 alpha-dehydroxylase activity of a gram-positive intestinal anaerobe by Bacteroides and its significance in the 7-dehydroxylation of ursodeoxycholic acid

The 7 alpha-dehydroxylation of chenodeoxycholic acid (CDCA) and cholic acid (CA) by a Eubacterium lentum-like intestinal anaerobe was specifically enhanced by the bacteroides present in mixed cultures and also by the addition to the growth medium of cell extracts from the bacteroides. The 7 alpha-de...

Full description

Bibliographic Details
Main Authors:	S Hirano, N Masuda
Format:	Article
Language:	English
Published:	Elsevier 1982-11-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520380524

Similar Items

7 beta-Dehydroxylation of ursodeoxycholic acid by whole cells and cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 12708.
by: B A White, et al.
Published: (1982-01-01)

Hepatic 7 alpha-dehydroxylation of bile acid intermediates, and its significance for the pathogenesis of cerebrotendinous xanthomatosis.
by: S Skrede, et al.
Published: (1988-02-01)

7alpha-Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum.
by: E J Stellwag, et al.
Published: (1979-03-01)

Mechanism of intestinal 7 alpha-dehydroxylation of cholic acid: evidence that allo-deoxycholic acid is an inducible side-product.
by: PB Hylemon, et al.
Published: (1991-01-01)

Bacterial 7-dehydroxylation of cholic acid and allocholic acid
by: Victor Bokkenheuser, et al.
Published: (1969-07-01)

The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology
by: Jason M. Ridlon, et al.
Published: (2023-08-01)

Dehydroxylation of 16 alpha-hydroxyprogesterone by fecal flora of man and rat
by: V D Bokkenheuser, et al.
Published: (1981-01-01)

Epimerization of the 7-hydroxy group of bile acids by the combination of two kinds of microorganisms with 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activity, respectively.
by: S Hirano, et al.
Published: (1981-09-01)

7-Methyl bile acids: 7 beta-methyl-cholic acid inhibits bacterial 7-dehydroxylation of cholic acid and chenodeoxycholic acid in the hamster.
by: S Kuroki, et al.
Published: (1987-07-01)

Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut
by: Marius Vital, et al.
Published: (2019-01-01)

Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium
by: Jason M. Ridlon, et al.
Published: (2012-01-01)

In vitro transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal flora, with particular reference to the mutual conversion between the two bile acids.
by: S Hirano, et al.
Published: (1981-07-01)

The 7-α-dehydroxylation pathway: An integral component of gut bacterial bile acid metabolism and potential therapeutic target
by: Journey L. Wise, et al.
Published: (2023-01-01)

Evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for ursodeoxycholic acid, and 7 oxo- and 12 oxo- bile acids
by: L J Haeffner, et al.
Published: (1980-05-01)

Dehydroxylation of the serpentinite before its chemical treatment
by: Gabriel Sučik, et al.
Published: (2009-09-01)

Pneumocephalus in mixed aerobic and anaerobic (Bacteroides fragilis) meningitis
by: Subasree Ramakrishnan, et al.
Published: (2014-01-01)

BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7α-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704
by: Karin Lederballe Meibom, et al.
Published: (2024-12-01)

Synthesis of ursodeoxycholic acid by electrochemical stereoselective reduction of 7-ketolithocholic acid in aprotic solvents
by: Jinxue Shen, et al.
Published: (2021-08-01)

Ultrasound-mediated DNA transformation in thermophilic gram-positive anaerobes.
by: Lu Lin, et al.
Published: (2010-01-01)

Non-Isothermal Kinetic Analysis of the Dehydroxylation of Kaolinite in Dynamic Air Atmosphere
by: Ondro Tomáš, et al.
Published: (2017-06-01)

Dehydroxylation of Minerals of Gadisunkapur Area with Special Reference to FTIR and Thermal Study
by: Marularadhya C. Hiremath, A. Sreenivasa
Published: (2020-07-01)

Conversion of 7alpha-hydroxycholesterol and 7alpha-hydroxy-beta-sitosterol to 3alpha, 7alpha-dihydroxy- and 3alpha, 7alpha, 12alpha-trihydroxy-5beta-steroids in vitro.
by: L Aringer
Published: (1975-11-01)

Early intestinal <it>Bacteroides fragilis </it>colonisation and development of asthma
by: Goossens Herman, et al.
Published: (2008-09-01)

Dehydroxylation of Kaolinite and Halloysite-Rich Samples: An In Situ Study of the Texture and Structural Evolutions
by: Imane Daou, et al.
Published: (2023-11-01)

Probing the Dehydroxylation of Kaolinite and Halloysite by In Situ High Temperature X-ray Diffraction
by: Imane Daou, et al.
Published: (2020-05-01)

Dehydroxylation of Kaolinite Tunes Metal Oxide–Nanoclay Interactions for Enhancing Antibacterial Activity
by: Dongyue Wang, et al.
Published: (2022-08-01)

Study on synthesis of ursodeoxycholic acid by reduction of 7-ketolithocholic acid in double aprotic solvents and molecular simulations
by: Mohan Dai, et al.
Published: (2023-08-01)

Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages.
by: Wan-Kyu Ko, et al.
Published: (2017-01-01)

Mode of action and functional significance of 7alpha-hydroxypregnenolone stimulating locomotor activity
by: Shogo eHaraguchi, et al.
Published: (2011-08-01)

Formation of ursodeoxycholic acid from chenodeoxycholic acid in the human colon: studies of the role of 7-ketolithocholic acid as an intermediate.
by: H Fromm, et al.
Published: (1983-07-01)

Intestinal Collinsella may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate.
by: Masaaki Hirayama, et al.
Published: (2021-01-01)

EVALUATION OF ANTIBIOTIC SUSCEPTIBILITY OF ANAEROBIC PATHOGENS BACTEROIDES, PREVOTELLA AND FUSOBACTERIUM ISOLATED FROM CANCER PATIENTS
by: I. I. Shilnikova, et al.
Published: (2016-02-01)

Gram-positive anaerobic cocci guard skin homeostasis by regulating host-defense mechanisms
by: Danique A. van der Krieken, et al.
Published: (2023-04-01)

Identification of the alpha-enolase P46 in the extracellular membrane vesicles of Bacteroides fragilis
by: Thais Gonçalves Ferreira, et al.

The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives
by: Hannah Jobelius, et al.
Published: (2022-01-01)

Intestinal Bacteroides sp. Imbalance Associated With the Occurrence of Childhood Undernutrition in China
by: Dongfang Li, et al.
Published: (2019-11-01)

Smad7 as a positive regulator of intestinal inflammatory diseases
by: Giovanni Monteleone, et al.
Published: (2023-01-01)

BACTEROIDES SPP. – CLINICAL SIGNIFICANCE, ANTIBIOTIC RESISTANCE AND IDENTIFICATION METHODS
by: Sebastian Niestępski, et al.
Published: (2017-04-01)

Noncontiguous finished genome sequences and description of Bacteroides mediterraneensis sp. nov., Bacteroides ihuae sp. nov., Bacteroides togonis sp. nov., Bacteroides ndongoniae sp. nov., Bacteroides ilei sp. nov. and Bacteroides congonensis sp. nov. identified by culturomics
by: C. Andrieu, et al.
Published: (2018-11-01)

Epimerization of chenodeoxycholic acid to ursodeoxycholic acid by human intestinal lecithinase-lipase-negative Clostridia.
by: R Edenharder, et al.
Published: (1981-05-01)