Fitness Shifts the Balance of BDNF and IL-6 from Inflammation to Repair among People with Progressive Multiple Sclerosis

Fitness Shifts the Balance of BDNF and IL-6 from Inflammation to Repair among People with Progressive Multiple Sclerosis

Physical sedentarism is linked to elevated levels of circulating cytokines, whereas exercise upregulates growth-promoting proteins such as brain-derived neurotrophic factor (BDNF). The shift towards a ‘repair’ phenotype could protect against neurodegeneration, especially in diseases such as multiple...

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Bibliographic Details
Main Authors: Augustine Joshua Devasahayam, Liam Patrick Kelly, John Bradley Williams, Craig Stephen Moore, Michelle Ploughman
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
multiple sclerosis
rehabilitation
fitness
neurodegeneration
inflammation
biomarkers
Online Access:https://www.mdpi.com/2218-273X/11/4/504

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